泪膜稳定性与视疲劳关系的客观评估
Objective Evaluation of Relationship Between Tear Film Stability and Visual Fatigue.
作者信息
Watanabe Maki, Hirota Masakazu, Takigawa Ryusei, Kato Kanako, Ikeda Yuka
机构信息
Division of Orthoptics, Graduate School of Medical Care and Technology, Teikyo University, Itabashi-ku, Tokyo, Japan.
Department of Orthoptics, Faculty of Medical Technology, Teikyo University, Itabashi-ku, Tokyo, Japan.
出版信息
Clin Optom (Auckl). 2025 Jul 1;17:175-183. doi: 10.2147/OPTO.S522320. eCollection 2025.
PURPOSE
To investigate the relationship between tear film stability and visual fatigue using two objective measurements: the non-invasive tear film break-up time (NI-BUT) and the binocular fusion maintenance (BFM) test.
METHODS
Eleven young adult volunteers (age [mean ± standard deviation], 20.7 ± 1.4 years) participated in this study. The NI-BUT was determined using the distortion of the mire ring. BFM was assessed by measuring the transmittance of liquid crystals placed in front of the subject's non-dominant eye when binocular fusion was broken, and non-dominant eye was shifted to heterophoric. The volunteers were administered the NI-BUT and BFM before and after a 30-minute visual task.
RESULTS
NI-BUT (pre vs post: 9.12 ± 1.00 s vs 5.69 ± 3.11 s) was significantly shorter in the post-visual task than in the pre-visual task ( = 0.011). BFM (0.95 ± 0.09 vs 0.75 ± 0.16) was significantly lower in the post-visual task than in the pre-visual task ( = 0.012). The change in NI-BUT was significantly and positively correlated with the change in BFM ( = 0.385, = 0.042).
CONCLUSION
These objective findings support the association between tear film stability and visual fatigue.
目的
使用两种客观测量方法——无创泪膜破裂时间（NI-BUT）和双眼融合维持（BFM）测试，研究泪膜稳定性与视觉疲劳之间的关系。
方法
11名年轻成年志愿者（年龄[平均值±标准差]，20.7±1.4岁）参与了本研究。使用视标环的变形来测定NI-BUT。通过测量当双眼融合被打破且非优势眼转为隐斜时置于受试者非优势眼前的液晶的透光率来评估BFM。在一项30分钟的视觉任务前后，对志愿者进行NI-BUT和BFM测量。
结果
视觉任务后NI-BUT（任务前vs任务后：9.12±1.00秒vs 5.69±3.11秒）显著短于视觉任务前（P = 0.011）。视觉任务后BFM（0.95±0.09 vs 0.75±0.16）显著低于视觉任务前（P = 0.012）。NI-BUT的变化与BFM的变化显著正相关（r = 0.385，P = 0.042）。
结论
这些客观研究结果支持泪膜稳定性与视觉疲劳之间的关联。
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