Wei Yingqi, Fang Kai, Hou Rui, Xie Chen, Ma Aijuan, Dong Zhong
Beijing Center for Disease Prevention and Control, Beijing, China.
China CDC Wkly. 2025 May 16;7(20):690-694. doi: 10.46234/ccdcw2025.114.
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: As an indicator of aortic stiffening, elevated pulse pressure (PP) has been established as a marker of poor clinical outcomes.
WHAT IS ADDED BY THIS REPORT?: Compared with the lowest quartile of PP (<40 mmHg), mortality risk increased by 9.8%-23.9% among individuals with PP in the second to fourth quartiles. This association was particularly pronounced in females, adults aged 60-74 years, and overweight or obese individuals.
WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: Our findings emphasize the need to develop comprehensive PP early screening and effective management strategies to reduce mortality, especially among identified high-risk groups.
关于该主题已知的信息有哪些?:作为主动脉硬化的一个指标,脉压(PP)升高已被确立为临床预后不良的一个标志物。
本报告新增了哪些内容?:与PP最低四分位数组(<40 mmHg)相比,PP处于第二至第四四分位数组的个体死亡风险增加了9.8%-23.9%。这种关联在女性、60-74岁的成年人以及超重或肥胖个体中尤为明显。
对公共卫生实践有哪些启示?:我们的研究结果强调,需要制定全面的PP早期筛查和有效的管理策略以降低死亡率,尤其是在已确定的高危人群中。