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动脉导管未闭情况下的肺动脉瓣心内膜炎:一例罕见临床病例。

Pulmonary valve endocarditis in the setting of a patent ductus arteriosus: A rare clinical case.

作者信息

Nour El Houda Lamassab, El Ouafi Noha, Ismaili Nabila

机构信息

Faculty of Medicine and Pharmacy, Mohammed I University, Oujda, Morocco.

Department of Cardiology, Mohammed VI University Hospital/Mohammed I University, Oujda, Morocco.

出版信息

Radiol Case Rep. 2025 Jun 24;20(9):4545-4550. doi: 10.1016/j.radcr.2025.05.082. eCollection 2025 Sep.

DOI:10.1016/j.radcr.2025.05.082
PMID:40620541
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12226265/
Abstract

Isolated pulmonary valve (PV) endocarditis is an exceedingly rare entity, accounting for less than 2% of all infective endocarditis cases. Its diagnosis is often delayed due to nonspecific clinical features and the inherent difficulty in visualizing the pulmonary valve on standard transthoracic and transesophageal echocardiography. We report the case of a 43-year-old woman presenting with persistent fever and pulmonary symptoms, in whom transthoracic echocardiography revealed a mobile vegetation on the PV. Despite clear imaging, the diagnosis was initially delayed due to the low index of suspicion and the unusual location of the infection. Further investigation uncovered a silent patent ductus arteriosus (PDA), likely predisposing to endocardial seeding. This case underscores the importance of maintaining clinical vigilance for PV involvement, even in non-IV drug users, and highlights how echocardiography-when carefully interpreted-can reveal rare valvular pathology. Recognition of atypical sites of endocarditis is crucial for timely diagnosis and management.

摘要

孤立性肺动脉瓣心内膜炎是一种极为罕见的疾病,占所有感染性心内膜炎病例的比例不到2%。由于其临床特征不具特异性,且在标准经胸和经食管超声心动图检查中难以观察到肺动脉瓣,其诊断往往会延迟。我们报告了一例43岁女性患者,该患者出现持续发热和肺部症状,经胸超声心动图显示肺动脉瓣上有一个活动的赘生物。尽管影像学表现明确,但由于怀疑指数低以及感染部位不寻常,最初诊断延迟。进一步检查发现了一个无症状的动脉导管未闭(PDA),可能是心内膜感染的易感因素。该病例强调了即使在非静脉药物使用者中,对肺动脉瓣受累保持临床警惕的重要性,并突出了仔细解读超声心动图如何能够揭示罕见的瓣膜病变。认识到心内膜炎的非典型部位对于及时诊断和治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1203/12226265/8919bd30080c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1203/12226265/882f644a7a44/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1203/12226265/f61334c3823c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1203/12226265/90e174b63783/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1203/12226265/8919bd30080c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1203/12226265/882f644a7a44/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1203/12226265/f61334c3823c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1203/12226265/90e174b63783/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1203/12226265/8919bd30080c/gr4.jpg

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本文引用的文献

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Unusual Presentation of Patent Ductus Arteriosus in Elderly Patient.老年患者动脉导管未闭的不典型表现。
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Huge idiopathic pulmonary artery aneurysm.巨大特发性肺动脉瘤
Radiol Case Rep. 2017 Mar 9;12(2):236-239. doi: 10.1016/j.radcr.2017.01.023. eCollection 2017 Jun.
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Infective Endocarditis Involving the Pulmonary Valve.感染性心内膜炎累及肺动脉瓣。
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Multicenter USA Amplatzer patent ductus arteriosus occlusion device trial: initial and one-year results.美国多中心动脉导管未闭封堵器试验:初始及一年结果
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