Alabi Ayobami Oyetunji, Sayomi Bukola Adetutu, Oladibu Olanike Taye, Adetoye Mayowa Mary, Aderinto Nicholas, Akintunde Adeseye Abiodun
Department of Pediatrics and Child Health, Ladoke Akintola University of Technology (LAUTECH) Teaching Hospital, Ogbomoso, Oyo, Nigeria.
Department of Medicine and Surgery, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.
J Med Case Rep. 2025 Jun 18;19(1):280. doi: 10.1186/s13256-025-05241-y.
Right-sided infective endocarditis is a rare clinical entity, with isolated pulmonary valve infective endocarditis being extremely uncommon. Infective endocarditis carries a high mortality rate and significant complications, making early identification and prompt management crucial in improving outcomes. This case highlights an unusual presentation of right-sided infective endocarditis isolated to the pulmonic valve in a pediatric patient with no apparent preexisting heart disease.
A 7-year-old girl of Yoruba ethnicity presented with septicemic illness, congestive heart failure, and no evidence of congenital cardiac lesion, underlying valvular disease, or identifiable predisposing factors. She had underweight malnutrition, cachexia, and severe respiratory distress. Echocardiography, which was delayed due to resource limitations, ultimately revealed isolated myxomatous vegetation on the pulmonary valve, dilated right cardiac chambers, and pulmonary hypertension. Blood cultures grew Pseudomonas aeruginosa. The patient was managed with antimicrobial agents, an anticardiac failure regimen, antiplatelets, and supportive therapy. Management was complicated by financial constraints, which delayed optimal intervention.
Although isolated pulmonary valve infective endocarditis is rare in the pediatric population, particularly in the absence of identifiable heart disease, a high index of suspicion is essential. Early diagnosis via echocardiography and prompt, adequate treatment are crucial for favorable outcomes. Awareness of potential diagnostic delays and financial barriers can aid in optimizing timely intervention and improving prognosis.
右侧感染性心内膜炎是一种罕见的临床病症,孤立性肺动脉瓣感染性心内膜炎极为少见。感染性心内膜炎死亡率高且并发症严重,因此早期识别和及时处理对于改善预后至关重要。本病例突出显示了一名无明显先天性心脏病的儿科患者出现的孤立性肺动脉瓣右侧感染性心内膜炎的不寻常表现。
一名7岁的约鲁巴族女孩出现败血症、充血性心力衰竭,且无先天性心脏病变、潜在瓣膜疾病或可识别的诱发因素的证据。她体重不足、营养不良、恶病质且有严重的呼吸窘迫。由于资源限制,超声心动图检查延迟,最终显示肺动脉瓣有孤立性黏液瘤样赘生物、右心腔扩大和肺动脉高压。血培养结果为铜绿假单胞菌生长。该患者接受了抗菌药物、抗心力衰竭方案、抗血小板药物及支持治疗。经济限制使治疗复杂化,延误了最佳干预时机。
尽管孤立性肺动脉瓣感染性心内膜炎在儿科人群中罕见,尤其是在无明确心脏病的情况下,但高度的怀疑指数至关重要。通过超声心动图早期诊断并及时、充分治疗对于取得良好预后至关重要。认识到潜在的诊断延迟和经济障碍有助于优化及时干预并改善预后。