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经导管动脉栓塞术治疗巨大肾血管平滑肌脂肪瘤破裂所致自发性腹膜后出血。

Spontaneous retroperitoneal bleeding from rupture of a massive renal angiomyolipoma managed with transcatheter arterial embolization.

作者信息

Oweidat Majd, Alra'e Mohammed, Hassouneh Ammar W M, Sarahna Besan, Kattoush Ibrahim

机构信息

College of Medicine, Hebron University, Hebron, West Bank, Palestine.

Department of Radiology, Princess Alia Hebron Governmental Hospital, Hebron, West Bank, Palestine.

出版信息

Radiol Case Rep. 2025 Jun 24;20(9):4555-4560. doi: 10.1016/j.radcr.2025.04.127. eCollection 2025 Sep.

DOI:10.1016/j.radcr.2025.04.127
PMID:40620546
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12226262/
Abstract

Ruptured renal angiomyolipoma (AML) is a rare but potentially life-threatening condition requiring prompt diagnosis and intervention. We report the case of a young female who presented with acute left-sided abdominal pain and gross hematuria. She had a known diagnosis of a large left renal AML. Initial evaluation revealed stable vital signs and mild anemia. Contrast-enhanced computed tomography (CT) confirmed a ruptured AML with an associated hematoma but no active extravasation. The patient was admitted for conservative management and subsequently underwent transcatheter arterial embolization (TAE) 2 weeks later. Under ultrasound guidance, vascular access was obtained via the right common femoral artery, and superselective catheterization of the feeding arteries to the tumor was performed. Embolization was achieved using a Lipiodol-N-butyl cyanoacrylate (NBCA) glue mixture in a 1:5 ratio. Final angiography showed complete devascularization of the lesion. Follow-up contrast-enhanced CT showed hematoma resolution, reduced tumor size, and no evidence of residual bleeding or nontarget embolization. The patient experienced marked clinical improvement and remained stable on follow-up without recurrence of symptoms. This case highlights the importance of considering renal AML in the differential diagnosis of spontaneous retroperitoneal hemorrhage. It also demonstrates the value of imaging in diagnosis and follow-up, as well as the role of TAE as an effective intervention in selected cases while preserving renal function.

摘要

肾血管平滑肌脂肪瘤(AML)破裂是一种罕见但可能危及生命的疾病,需要及时诊断和干预。我们报告一例年轻女性病例,该患者出现急性左侧腹痛和肉眼血尿。她已知患有左侧巨大肾AML。初步评估显示生命体征稳定,有轻度贫血。增强计算机断层扫描(CT)证实AML破裂并伴有血肿,但无活动性造影剂外渗。患者入院接受保守治疗,两周后接受了经导管动脉栓塞术(TAE)。在超声引导下,通过右股总动脉获得血管通路,并对肿瘤供血动脉进行超选择性插管。使用碘油-正丁基氰基丙烯酸酯(NBCA)胶水混合物按1:5的比例进行栓塞。最终血管造影显示病变完全去血管化。随访增强CT显示血肿消退、肿瘤大小缩小,且无残留出血或非靶栓塞的证据。患者临床症状明显改善,随访期间保持稳定,无症状复发。该病例突出了在自发性腹膜后出血的鉴别诊断中考虑肾AML的重要性。它还展示了影像学在诊断和随访中的价值,以及TAE作为一种在保留肾功能的情况下对特定病例有效的干预措施的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ecf/12226262/33a42a55f5cb/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ecf/12226262/229f3ddad81e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ecf/12226262/1349a1b761f8/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ecf/12226262/3d531c3247b9/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ecf/12226262/33a42a55f5cb/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ecf/12226262/229f3ddad81e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ecf/12226262/1349a1b761f8/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ecf/12226262/3d531c3247b9/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ecf/12226262/33a42a55f5cb/gr4.jpg

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本文引用的文献

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A Case of Life-threatening Rupture of Small Renal Angiomyolipoma with an Unidentified Intratumoral Aneurysm during Follow-up.一例随访期间小肾血管平滑肌脂肪瘤破裂伴瘤内不明动脉瘤致生命危险的病例。
Interv Radiol (Higashimatsuyama). 2024 Feb 8;9(1):20-25. doi: 10.22575/interventionalradiology.2023-0013. eCollection 2024 Mar 1.
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Renal Angiomyolipoma Rupture Following COVID-19 Infection: A Case Report.新型冠状病毒肺炎感染后肾血管平滑肌脂肪瘤破裂:一例报告
Cureus. 2023 Jul 11;15(7):e41734. doi: 10.7759/cureus.41734. eCollection 2023 Jul.
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New Trends and Evidence for the Management of Renal Angiomyolipoma: A Comprehensive Narrative Review of the Literature.
肾血管平滑肌脂肪瘤管理的新趋势与证据:文献综述
J Kidney Cancer VHL. 2022 Jan 21;9(1):33-41. doi: 10.15586/jkcvhl.v9i1.177. eCollection 2022.
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Key Renal Neoplasms With a Female Predominance.女性为主的主要肾脏肿瘤。
Adv Anat Pathol. 2021 Jul 1;28(4):228-250. doi: 10.1097/PAP.0000000000000301.
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Canadian Urological Association best practice report: Diagnosis and management of sporadic angiomyolipomas.加拿大泌尿外科协会最佳实践报告:散发性肾血管平滑肌脂肪瘤的诊断与管理
Can Urol Assoc J. 2020 Nov;14(11):E527-E536. doi: 10.5489/cuaj.6942.
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