Brewster M A, Heim M A
Ann Clin Lab Sci. 1985 Nov-Dec;15(6):470-4.
Adverse reproductive outcomes were sought via medical records of 14 central Arkansas hospitals serving a five county area encompassing 28, 102 live births in the 1980 to 1982 study period. This population-based study estimated the overall congenital anomaly case incidence to be 3.5 percent of live births. Information on pregnancy history of the cases or on parental occupations was often not recorded in the medical records of infant or mother, precluding the use of these records for many etiologic investigations. Fetal wastage cases found through hospital sources encompassed 86 percent of the number reported to the Department of Health. Autopsies were performed in only 16 percent of fetal death cases. Many of the fetal death cases not subjected to autopsy had no apparent cause of death listed; reasons for this lack of investigation warrant further study. These pregnancy outcome data have been correlated with agricultural pesticide usage and can be examined in a variety of environmental contexts for development and testing of etiologic hypotheses.
通过阿肯色州中部14家医院的病历，对1980年至1982年研究期间涵盖五个县、共28102例活产的地区进行了不良生殖结局调查。这项基于人群的研究估计，先天性异常病例的总体发病率为活产的3.5%。病例的妊娠史或父母职业信息在婴儿或母亲的病历中常常未被记录，这使得这些病历无法用于许多病因学调查。通过医院渠道发现的胎儿流产病例占向卫生部报告数量的86%。仅16%的胎儿死亡病例进行了尸检。许多未进行尸检的胎儿死亡病例没有列出明显的死因；缺乏调查的原因值得进一步研究。这些妊娠结局数据已与农业农药使用情况相关联，并且可以在各种环境背景下进行检查，以形成和检验病因学假设。
