Kira Shinichiro, Zylberberg Ariel, Shadlen Michael N
Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115.
Zuckerman Mind Brain Behavior Institute, Columbia University, New York, New York 10027.
J Neurosci. 2025 Jul 30;45(31):e2426242025. doi: 10.1523/JNEUROSCI.2426-24.2025.
Many decisions benefit from the accumulation of evidence obtained sequentially over time. In such circumstances, the decision-maker must balance speed against accuracy, while considering the cost associated with the passage of time. A neural mechanism to achieve this balance is to accumulate evidence and to terminate the deliberation when enough evidence has accrued. To accommodate time costs, it has been hypothesized that the criterion to terminate a decision may become lax as a function of time. Here we tested this hypothesis by manipulating the cost of time in a perceptual choice-reaction time (RT) task. Human participants (both sexes) discriminated the direction of motion in a dynamic random-dot display, which varied in difficulty across trials. Unbeknownst to the participants, halfway through the experiment, we increased the time pressure by canceling a small fraction of trials, mimicking a broken fixation, if they had not made a decision by a provisional deadline. This subtle manipulation led participants to make faster but less accurate decisions. Choice and RT were well explained by a bounded evidence-accumulation process. We developed a novel computational method to estimate the time-dependent changes in the stopping bounds directly from the participants' RT and choice data. Our analysis revealed that the bounds decline as a function of time, and that this decline is steeper following the time-cost manipulation. The time-varying decision bounds approximate an optimal stopping policy, although the specific bound shape is idiosyncratic across individuals.
许多决策受益于随着时间依次积累的证据。在这种情况下,决策者必须在速度与准确性之间进行权衡,同时考虑与时间流逝相关的成本。实现这种平衡的一种神经机制是积累证据,并在积累了足够的证据时终止审议。为了适应时间成本,有人假设终止决策的标准可能会随着时间的推移而变得宽松。在这里,我们通过在感知选择反应时(RT)任务中操纵时间成本来检验这一假设。人类参与者(男女皆有)在动态随机点显示中辨别运动方向,每次试验的难度各不相同。参与者并不知道,在实验进行到一半时,如果他们在临时截止日期前没有做出决定,我们会取消一小部分试验来增加时间压力,模拟注视中断。这种微妙的操纵导致参与者做出更快但准确性更低的决策。选择和反应时可以通过有界证据积累过程得到很好的解释。我们开发了一种新颖的计算方法,直接从参与者的反应时和选择数据中估计停止边界随时间的变化。我们的分析表明,边界随着时间的推移而下降,并且在时间成本操纵之后这种下降更为陡峭。尽管具体的边界形状因人而异,但随时间变化的决策边界近似于最优停止策略。