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双相情感障碍心境正常患者的残疾与社会认知

Disability and social cognition in euthymic patients with bipolar disorder.

作者信息

Sevindik Muhammet, Demir Aybüke, Erdem Elif, Nazlı Şerif Bora

机构信息

Faculty of Medicine, Department of Psychiatry, Ordu University, Ordu, Türkiye.

Cumhuriyet Mahallesi, Mustafa Kemal Boulevard No:254, Altınordu, Ordu University, Cumhuriyet Campus Faculty of Medicine, Ordu, 52200, Türkiye.

出版信息

BMC Psychiatry. 2025 Jul 7;25(1):686. doi: 10.1186/s12888-025-07119-1.

Abstract

BACKGROUND

Cognitive performance is known to influence the functional level of psychiatric disorders in both the short and long term. This study aims to examine disability, social cognition, and the clinical and sociodemographic variables affecting both in individuals diagnosed with bipolar disorder (BD) during the euthymic phase.

METHODS

This cross-sectional study included 62 euthymic patients diagnosed with BD who attended the Mood Disorders Outpatient Clinic of the Psychiatry Department and agreed to participate. Data collection involved a sociodemographic information form, the Reading the Mind in the Eyes Test (RMET) and the Basic Empathy Scale (BES) to assess social cognition, and the World Health Organization Disability Assessment Schedule 2.0 (WHODAS-2) to evaluate disability.

RESULTS

A significant positive correlation was identified between RMET scores and educational level (r = 0.320, p < 0.05). Regression analysis revealed that age (β=-0.284; p = 0.025) and social support(β=-0.310; p = 0.008) had a significant negative impact on WHODAS-2 total scores, whereas having a first episode of depression compared to a first episode of mania had a significant positive impact on WHODAS-2 total scores (β = 0.281; p = 0.025).

CONCLUSION

The findings suggest that the onset of BD with a depressive episode and the lack of social support may be associated with disability even in the euthymic phase. The significant negative association between age and disability implies that increased awareness through psychoeducation and the development of appropriate coping strategies may contribute to reduced disability in later life. These results highlight the importance of early intervention and supportive factors in the management of BD.

摘要

背景

认知表现已知会在短期和长期内影响精神疾病的功能水平。本研究旨在检查双相情感障碍(BD)患者在心境正常期的残疾情况、社会认知以及影响二者的临床和社会人口统计学变量。

方法

这项横断面研究纳入了62名被诊断为BD且处于心境正常期的患者,他们在精神科的心境障碍门诊就诊并同意参与。数据收集包括一份社会人口统计学信息表、用于评估社会认知的“眼神读心测试”(RMET)和“基本共情量表”(BES),以及用于评估残疾情况的世界卫生组织残疾评估量表2.0(WHODAS - 2)。

结果

RMET得分与教育水平之间存在显著正相关(r = 0.320,p < 0.05)。回归分析显示,年龄(β = -0.284;p = 0.025)和社会支持(β = -0.310;p = 0.008)对WHODAS - 2总分有显著负面影响,而与首次躁狂发作相比,首次抑郁发作对WHODAS - 2总分有显著正面影响(β = 0.281;p = 0.025)。

结论

研究结果表明,即使在心境正常期,以抑郁发作为起始的BD以及缺乏社会支持可能与残疾相关。年龄与残疾之间的显著负相关意味着通过心理教育提高认识和制定适当的应对策略可能有助于降低晚年的残疾程度。这些结果突出了早期干预和支持因素在BD管理中的重要性。

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