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多学科康复护理在布鲁氏菌性脊柱炎患者中的应用及其对疼痛、炎症和免疫功能的影响

Application of Multidisciplinary Rehabilitation Nursing in Patients with Brucellar Spondylitis and Its Effects on Pain, Inflammation, and Immune Function.

作者信息

Zhang Ying, Zuo Xianhong, Yang Xiao, Li Rui, Wang Huan, Yu Jiantao, Yang Xinming

机构信息

Department of Orthopedics, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei Province, 075000, People's Republic of China.

School of Nursing, Zhangjiakou University, Zhangjiakou, Hebei, 075000, People's Republic of China.

出版信息

J Multidiscip Healthc. 2025 Jul 2;18:3813-3826. doi: 10.2147/JMDH.S528741. eCollection 2025.

DOI:10.2147/JMDH.S528741
PMID:40625556
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12230325/
Abstract

OBJECTIVE

This study evaluated the effects of multidisciplinary rehabilitation nursing on postoperative outcomes in patients with brucellar spondylitis, focusing on pain, inflammation, immune function, emotional state, sleep quality, spinal mobility, adverse reactions, and patient satisfaction.

METHODS

A retrospective analysis was conducted on 87 patients who underwent surgery for brucellar spondylitis between January 2020 and June 2024. Patients were divided into two groups: the Routine Group (n=43, receiving standard nursing care) and the Combined Group (n=44, receiving additional multidisciplinary rehabilitation nursing). Outcomes were assessed using the Visual Analog Scale (VAS), inflammatory markers (CRP, ESR, WBC), immune indicators (CD4+, CD8+, CD4+/CD8+), emotional scales (SAS, SDS), sleep quality (PSQI), spinal function (ODI), incidence of adverse reactions, and satisfaction (NSNS).

RESULTS

The combined group exhibited significantly greater improvements than the routine group across most parameters. Postoperative pain (VAS) decreased more markedly at days 1 and 7. Inflammatory markers (CRP, ESR, WBC) and immune function (increased CD4+, CD4+/CD8+ and decreased CD8+) improved significantly by postoperative day 7, particularly in the combined group. Psychological status (SAS, SDS), sleep quality (PSQI), and spinal mobility (ODI) also improved more in the combined group. Adverse reaction rates were comparable between groups. However, patient satisfaction was significantly higher in the combined group (89.13%) than in the routine group (71.74%).

CONCLUSION

Multidisciplinary rehabilitation nursing, when integrated with conventional care, significantly improves pain control, inflammatory response, immune function, emotional well-being, sleep quality, and spinal mobility in patients with brucellar spondylitis, without increasing adverse events, and results in higher patient satisfaction.

摘要

目的

本研究评估多学科康复护理对布鲁氏菌性脊柱炎患者术后结局的影响,重点关注疼痛、炎症、免疫功能、情绪状态、睡眠质量、脊柱活动度、不良反应及患者满意度。

方法

对2020年1月至2024年6月间接受布鲁氏菌性脊柱炎手术的87例患者进行回顾性分析。患者分为两组:常规组(n = 43,接受标准护理)和联合组(n = 44,接受额外的多学科康复护理)。采用视觉模拟量表(VAS)、炎症标志物(CRP、ESR、WBC)、免疫指标(CD4⁺、CD8⁺、CD4⁺/CD8⁺)、情绪量表(SAS、SDS)、睡眠质量(PSQI)、脊柱功能(ODI)、不良反应发生率及满意度(NSNS)对结局进行评估。

结果

联合组在大多数参数上的改善明显大于常规组。术后第1天和第7天,术后疼痛(VAS)下降更为明显。术后第7天,炎症标志物(CRP、ESR、WBC)和免疫功能(CD4⁺、CD4⁺/CD8⁺升高,CD8⁺降低)显著改善,联合组尤为明显。联合组的心理状态(SAS、SDS)、睡眠质量(PSQI)和脊柱活动度(ODI)也有更大改善。两组不良反应发生率相当。然而,联合组患者满意度(89.13%)显著高于常规组(71.74%)。

结论

多学科康复护理与传统护理相结合,可显著改善布鲁氏菌性脊柱炎患者的疼痛控制、炎症反应、免疫功能、情绪健康、睡眠质量和脊柱活动度,且不增加不良事件的发生,并提高患者满意度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/902b/12230325/412a0ec7013c/JMDH-18-3813-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/902b/12230325/5ea74bb834f0/JMDH-18-3813-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/902b/12230325/bfea1ba8f8df/JMDH-18-3813-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/902b/12230325/31a23ab5a838/JMDH-18-3813-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/902b/12230325/412a0ec7013c/JMDH-18-3813-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/902b/12230325/5ea74bb834f0/JMDH-18-3813-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/902b/12230325/bfea1ba8f8df/JMDH-18-3813-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/902b/12230325/31a23ab5a838/JMDH-18-3813-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/902b/12230325/412a0ec7013c/JMDH-18-3813-g0004.jpg

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