Stepanova E O, Iushkantseva S I
Arkh Anat Gistol Embriol. 1985 Sep;89(9):37-43.
Rhythmical changes in the activity of the neurosecretory processes have been compared in the supraoptic (SON) and paraventricular (PVN) nuclei in the C57Bl mice hypothalamus during vernal equinox. Parts of the neurosecretory cells, being at stages of synthesis, excretion and accumulation of secrete, volumes of the cell nuclei and nucleoli survey as criteria of their activity. Similar feature for the rhythmic of both nuclei studied is the highest activation of the processes during day time, when mice are resting; this is demonstrated as the maximal amount of actively synthesizing cells, maximal volumes of the cell nuclei and nucleoli. The peculiarities of the rhythmic display in the activity is manifested as a greater ability of the SON cells to accumulate neurosecrete. The accumulation of the secretory material in the SON cells precedes to the period of its maximal activity (1-7 PM) characterized: by making the cells free from the secrete and by a maximal increasing the volume of the nucleoli. In the PVN intensified display of the activity is noted at early hours of the day, and the amount of the cells not containing the secrete--at 6 PM. Lack of the neurosecrete accumulation in the PVN cells speaks in favour of more steady than in the SON cells excretion of the secrete. This demonstrates a more even maintenance of neurohormones concentration in the organism.
在春分时节，对C57Bl小鼠下丘脑视上核（SON）和室旁核（PVN）中神经分泌过程活动的节律变化进行了比较。以处于分泌合成、排泄和积累阶段的部分神经分泌细胞、细胞核和核仁的体积测量作为其活动的标准。所研究的两个核的节律的相似特征是在白天小鼠休息时过程的最高激活；这表现为活跃合成细胞的最大数量、细胞核和核仁的最大体积。活动中节律表现的特点是SON细胞积累神经分泌的能力更强。SON细胞中分泌物质的积累先于其最大活动期（下午1点至7点），其特征是细胞内无分泌物质且核仁体积最大增加。在PVN中，活动的增强显示在一天的早些时候，而不含分泌物质的细胞数量在下午6点时最多。PVN细胞中缺乏神经分泌积累表明其分泌比SON细胞更稳定。这表明机体中神经激素浓度的维持更为均匀。
