Li Ziyu, Li Gefang, Wu Jun, He Bo, Zhang Qun
Children's Hospital of Chongqing Medical University Chongqing China.
Department of Pediatric Orthopedics Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics Chongqing China.
Pediatr Discov. 2025 Jan 10;3(1):e2522. doi: 10.1002/pdi3.2522. eCollection 2025 Mar.
Septic arthritis is a serious infectious disease in children. In this study, we retrospectively analyzed the relationship between demographics, laboratory values at presentation, reported symptoms at presentation, joint involvement, and distribution characteristics of pathogenic bacteria in 171 patients during the period of 2012-2022. The results showed that a total of 77 pathogen-positive patients were detected in the 171 patients (culture-positive rate of 45.0%), 15 categories of pathogenic bacteria, and the highest detection rates were 52 cases of (67.5%), in 7 cases (9.1%), and in 5 cases (6.5%). Comparison of these three pathogens revealed that the age of the and groups was significantly older than that of the group ( < 0.05), and that the white blood cell count (WBC) of the group was significantly higher than that of the group ( < 0.05), and that the group had a significantly higher procalcitonin (PCT), which was significantly higher in the group ( < 0.05). The results suggest that the pathogenic bacteria of septic arthritis in children are mainly , infection occurred more commonly in the infant stage, and and were detected frequently in school-age children. was found to be more pathogenic than and .
化脓性关节炎是儿童的一种严重传染病。在本研究中，我们回顾性分析了2012年至2022年期间171例患者的人口统计学特征、就诊时的实验室检查值、就诊时报告的症状、关节受累情况以及病原菌的分布特征。结果显示，171例患者中共检测出77例病原菌阳性患者（培养阳性率为45.0%），病原菌有15种，检出率最高的是[具体细菌1]52例（67.5%），[具体细菌2]7例（9.1%），[具体细菌3]5例（6.5%）。对这三种病原菌进行比较发现，[具体细菌1]组和[具体细菌2]组的年龄显著大于[具体细菌3]组（P<0.05），[具体细菌1]组的白细胞计数（WBC）显著高于[具体细菌3]组（P<0.05），[具体细菌1]组的降钙素原（PCT）显著更高，在[具体细菌2]组中也显著更高（P<0.05）。结果表明，儿童化脓性关节炎的病原菌主要是[具体细菌1]，[具体细菌2]感染在婴儿期更为常见，[具体细菌1]和[具体细菌3]在学龄儿童中检出频率较高。发现[具体细菌1]比[具体细菌2]和[具体细菌3]的致病性更强。
