来自水母发光蛋白的证据表明，代谢受抑制的心肌细胞会受到损伤，且这种损伤与游离钙离子无关。
Evidence from aequorin for injury of metabolically inhibited myocytes independently of free Ca2+.
作者信息
Cobbold P H, Bourne P K, Cuthbertson S R
出版信息
Basic Res Cardiol. 1985;80 Suppl 2:155-8.
PMID:4062828
Abstract
The calcium-sensitive photoprotein aequorin has been used to measure cytoplasmic free Ca in single rat ventricle myocytes during metabolic inhibition. Rounding-up of the myocytes, and blebbing of the surface, occurred while free Ca remained at normal resting levels of 1 to 3 X 10(-7)M. Control over free Ca is less susceptible to metabolic blockade than is structural organization.
摘要
钙敏感光蛋白水母发光蛋白已被用于在代谢抑制期间测量单个大鼠心室肌细胞中的细胞质游离钙。在游离钙保持在1至3×10（-7）M的正常静息水平时，肌细胞出现变圆以及表面起泡现象。与结构组织相比，对游离钙的控制对代谢阻断更不敏感。
相似文献
1
Evidence from aequorin for injury of metabolically inhibited myocytes independently of free Ca2+.来自水母发光蛋白的证据表明，代谢受抑制的心肌细胞会受到损伤，且这种损伤与游离钙离子无关。
Basic Res Cardiol. 1985;80 Suppl 2:155-8.
2
[Measurement of Ca++ transients in muscle cells with aequorin (author's transl)].用水母发光蛋白测量肌肉细胞中的钙离子瞬变（作者译）
Nihon Seirigaku Zasshi. 1982;44(2):37-48.
3
Aequorin measurements of free calcium in single heart cells.单个心肌细胞中游离钙的水母发光蛋白测量法
Nature. 1984;312(5993):444-6. doi: 10.1038/312444a0.
4
Effects of strophanthidin on intracellular calcium concentration in ventricular myocytes of guinea pig.毒毛花苷元对豚鼠心室肌细胞内钙浓度的影响。
Yao Xue Xue Bao. 2008 Mar;43(3):259-66.
5
Practical aspects of the use of photoproteins as biological calcium indicators.
Soc Gen Physiol Ser. 1986;40:229-38.
6
Altered ionic calcium and cell motion in ventricular myocytes after cutaneous thermal injury.皮肤热损伤后心室肌细胞中离子钙和细胞运动的改变
J Surg Res. 1997 Mar;68(2):133-8. doi: 10.1006/jsre.1997.5032.
7
Effects of praeruptorine C on the intracellular free calcium in normal and hypertrophied rat ventricular myocytes.
Zhongguo Yao Li Xue Bao. 1997 May;18(3):251-4.
8
The role of sarcoplasmic reticulum and Na-Ca exchange in the Ca2+ extrusion from the resting myocytes of guinea-pig heart: comparison with rat.肌浆网和钠钙交换在豚鼠心脏静息心肌细胞钙外流中的作用：与大鼠的比较。
J Mol Cell Cardiol. 1993 Jan;25(1):75-91. doi: 10.1006/jmcc.1993.1009.
9
Intracellular Ca2+ shifts during the Ca2+ paradox.钙反常期间细胞内钙离子的转移
Basic Res Cardiol. 1985;80 Suppl 2:25-30.
10
引用本文的文献
1
Phorbol-ester-induced alterations of free calcium ion transients in single rat hepatocytes.佛波酯诱导的单个大鼠肝细胞中游离钙离子瞬变的改变。
Biochem J. 1987 Sep 15;246(3):619-23. doi: 10.1042/bj2460619.
Zotero 插件