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无声却致命:一例钝缘支动脉闭塞病例

Silent but Deadly: A Case of Obtuse Marginal Artery Occlusion.

作者信息

Miller Austin M, Tharani Vishal, Fraser Erin, Levitin Howard W

机构信息

Emergency Medicine, OhioHealth Doctors Hospital, Columbus, USA.

出版信息

Cureus. 2025 Jun 8;17(6):e85561. doi: 10.7759/cureus.85561. eCollection 2025 Jun.

DOI:10.7759/cureus.85561
PMID:40630366
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12236989/
Abstract

The obtuse marginal artery (OMA) is a key branch of the left circumflex coronary artery, supplying blood to the lateral wall of the left ventricle. OMA occlusions can result in myocardial ischemia and serious cardiac events, often presenting with subtle or atypical electrocardiogram (EKG) changes, unlike the more pronounced alterations observed with left anterior descending artery occlusions. This case report discusses a 57-year-old female presenting with chest pain and shortness of breath, indicative of acute coronary syndrome. The patient's initial EKG showed occasional premature ventricular contractions (PVCs), T-wave flattening in aVL, and 1 mm ST elevation in V6, but otherwise, it was normal appearing. Despite not having typical EKG abnormalities, the patient suffered a cardiac arrest. Coronary angiography confirmed 100% stenosis of the first OMA branch, which was successfully treated with aspiration thrombectomy and stent placement. The patient did not have collateral coronary vessels, and therefore, did not have a role in making the patient's EKGs difficult to interpret. This case emphasizes the challenges posed by OMA occlusions, underscoring the necessity for a high index of suspicion during the early stages of a patient's presentation for prompt diagnosis and treatment.

摘要

钝缘支动脉(OMA)是左旋冠状动脉的一个关键分支,为左心室侧壁供血。OMA闭塞可导致心肌缺血和严重的心脏事件,通常表现为细微或不典型的心电图(EKG)变化,这与左前降支动脉闭塞时观察到的更明显变化不同。本病例报告讨论了一名57岁女性,出现胸痛和呼吸急促,提示急性冠状动脉综合征。患者最初的心电图显示偶尔出现室性早搏(PVC),aVL导联T波低平,V6导联ST段抬高1mm,但其他方面看起来正常。尽管没有典型的心电图异常,患者仍发生了心脏骤停。冠状动脉造影证实第一支OMA分支100%狭窄,通过抽吸血栓切除术和支架置入成功治疗。患者没有冠状动脉侧支血管,因此,这并非导致患者心电图难以解读的原因。本病例强调了OMA闭塞带来的挑战,突出了在患者就诊早期保持高度怀疑指数以进行及时诊断和治疗的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb47/12236989/99fefe30ad1b/cureus-0017-00000085561-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb47/12236989/ae66481e3719/cureus-0017-00000085561-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb47/12236989/59ab540c3475/cureus-0017-00000085561-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb47/12236989/1b6a907260f1/cureus-0017-00000085561-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb47/12236989/99fefe30ad1b/cureus-0017-00000085561-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb47/12236989/ae66481e3719/cureus-0017-00000085561-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb47/12236989/59ab540c3475/cureus-0017-00000085561-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb47/12236989/1b6a907260f1/cureus-0017-00000085561-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb47/12236989/99fefe30ad1b/cureus-0017-00000085561-i04.jpg

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本文引用的文献

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From ST-Segment Elevation MI to Occlusion MI: The New Paradigm Shift in Acute Myocardial Infarction.从ST段抬高型心肌梗死到闭塞性心肌梗死:急性心肌梗死的新范式转变
JACC Adv. 2024 Oct 8;3(11):101314. doi: 10.1016/j.jacadv.2024.101314. eCollection 2024 Nov.
2
Systematic review and meta-analysis of diagnostic test accuracy of ST-segment elevation for acute coronary occlusion.ST段抬高对急性冠状动脉闭塞诊断试验准确性的系统评价和荟萃分析。
Int J Cardiol. 2024 May 1;402:131889. doi: 10.1016/j.ijcard.2024.131889. Epub 2024 Feb 20.
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New ECG Algorithm for the Prediction of Culprit Vessel in Acute Myocardial Infarction Involving Lateral Part of the Ventricle: Ilkay Classification.
用于预测累及心室侧壁的急性心肌梗死罪犯血管的新型心电图算法:伊尔凯分类法
Int J Gen Med. 2023 Jun 22;16:2643-2651. doi: 10.2147/IJGM.S416376. eCollection 2023.
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Case report of non-ST-segment elevation myocardial infarction diagnosed in spectral detector-based computed tomography performed for the diagnosis of acute pulmonary embolism.在为诊断急性肺栓塞而进行的基于光谱探测器的计算机断层扫描中诊断出非ST段抬高型心肌梗死的病例报告。
Eur Heart J Case Rep. 2020 Sep 9;4(5):1-7. doi: 10.1093/ehjcr/ytaa284. eCollection 2020 Oct.
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ST-Elevation Myocardial Infarction (STEMI) in a Patient with Moyamoya Disease.烟雾病患者的ST段抬高型心肌梗死(STEMI)
Case Rep Cardiol. 2019 Feb 4;2019:7124072. doi: 10.1155/2019/7124072. eCollection 2019.
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Impact of total occlusion of culprit artery in acute non-ST elevation myocardial infarction: a systematic review and meta-analysis.罪犯动脉完全闭塞对急性非 ST 段抬高型心肌梗死的影响:系统评价和荟萃分析。
Eur Heart J. 2017 Nov 1;38(41):3082-3089. doi: 10.1093/eurheartj/ehx418.
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