Liu Jiahui, Sun Kun, Deng Yanxia, Ding Lianshu
Department of Neurosurgery, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Nanjing Medical University, Huai'an, Jiangsu, China.
Front Med (Lausanne). 2025 Jun 24;12:1600412. doi: 10.3389/fmed.2025.1600412. eCollection 2025.
Cerebral syphilitic gumma, a rare form of neurosyphilis, poses significant diagnostic challenges due to its imaging similarities to gliomas and brain metastases. This report details the diagnostic and therapeutic journey of a patient with cerebral syphilitic gumma admitted to the Department of Neurosurgery, Nanjing Medical University Affiliated Huaian First Hospital in February 2025. Initially misdiagnosed with a brain malignancy, the accurate diagnosis was established intraoperatively and confirmed postoperatively through histopathological examination. This case highlights the importance of considering neurosyphilis in differential diagnoses of intracranial lesions, especially when conventional imaging and clinical presentations are inconclusive.
脑梅毒瘤是神经梅毒的一种罕见形式，由于其影像学表现与胶质瘤和脑转移瘤相似，给诊断带来了重大挑战。本报告详细介绍了一名于2025年2月入住南京医科大学附属淮安第一医院神经外科的脑梅毒瘤患者的诊断和治疗过程。该患者最初被误诊为脑恶性肿瘤，术中得以明确诊断，并在术后通过组织病理学检查得到证实。该病例强调了在颅内病变的鉴别诊断中考虑神经梅毒的重要性，尤其是当传统影像学和临床表现不明确时。
