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Primary structures of locust adipokinetic hormones II.

作者信息

Siegert K, Morgan P, Mordue W

出版信息

Biol Chem Hoppe Seyler. 1985 Aug;366(8):723-7. doi: 10.1515/bchm3.1985.366.2.723.

DOI:10.1515/bchm3.1985.366.2.723
PMID:4063072
Abstract

Adipokinetic hormones II from corpora cardiaca of the locusts Schistocerca gregaria and Locusta migratoria, respectively, have been isolated and their primary structures elucidated. Both octapeptides are N-terminally blocked by a 5-oxoproline (pyroglutamate) residue and had to be cleaved by 5-oxoprolyl-peptidase to make them available for the Edman degradation method carried out with a gas-phase sequencer. The C-termini are blocked as both peptides are not cleaved by carboxypeptidase A; the presence of C-terminal amide groups is very likely. AKHII (S. gregaria) Glu-Leu-Asn-Phe-Ser-Thr-Gly-Trp-NH2 AKHII (L. migratoria) Glu-Leu-Asn-Phe-Ser-Ala-Gly-Trp-NH2.

摘要

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