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飞蝗脂肪动激素的结构,一种在飞行过程中调节脂质利用的神经激素。

Structure of locust adipokinetic hormone, a neurohormone that regulates lipid utilisation during flight.

作者信息

Stone J V, Mordue W, Batley K E, Morris H R

出版信息

Nature. 1976 Sep 16;263(5574):207-11. doi: 10.1038/263207a0.

DOI:10.1038/263207a0
PMID:958472
Abstract

Adipokinetic hormone, isolated from locust corpora cardiaca, has been identified as a blocked peptide: PCA-Leu-Asn-Phe-Thr-Pro-Asn-Trp-Gly-Thr-NH2. The detailed structure is based on mass spectrometric data, substantiated in part by dansyl-Edman and carboxypeptidase data on thermolytic fragments. This is the first peptide hormone from an insect neuroendocrine organ to be fully characterised.

摘要

从蝗虫心侧体中分离出的脂肪动激素已被鉴定为一种受阻肽

PCA-亮氨酸-天冬酰胺-苯丙氨酸-苏氨酸-脯氨酸-天冬酰胺-色氨酸-甘氨酸-苏氨酸-NH2。详细结构基于质谱数据,部分由丹磺酰-埃德曼法和关于热解片段的羧肽酶数据证实。这是首个得到充分表征的来自昆虫神经内分泌器官的肽激素。

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Nature. 1976 Sep 16;263(5574):207-11. doi: 10.1038/263207a0.
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