Muenkaew Yosita, Jinawath Artit, Cheewaruangroj Wichit
Department of Otolaryngology-Head & Neck Surgery, Ramathibodi Hospital, Faculty of Medicine, Mahidol University, Bangkok, Thailand.
Department of Pathology, Ramathibodi Hospital, Faculty of Medicine, Mahidol University, Bangkok, Thailand.
Cancer Rep (Hoboken). 2025 Jul;8(7):e70270. doi: 10.1002/cnr2.70270.
Chordomas are rare tumors that arise from notochord remnants and are typically located in the axial skeleton. Chordomas arising in the lower cervical spine are rare.
We report a case of a 79-year-old man who presented with a lump on the left side of his neck, indicating an unusual presentation of a chordoma in the lower cervical region. This report describes the clinical, radiological, and histological results of this patient who sought medical attention for a left-sided neck mass. Additional diagnostic tests, including immunohistochemistry and biopsy, confirmed the existence of a chordoma affecting the lower cervical region.
The precision of a diagnosis of cervical chordoma hinges on imaging study results and confirmation provided by histological examination, typically through biopsy and immunohistochemistry. The primary treatment for cervical chordoma is the surgical resection. Adjunctive therapies, such as radiation therapy and, in some cases, chemotherapy, may be used to manage residual disease or recurrent tumors.
This case emphasizes the rarity of lower cervical chordomas, which present as a neck mass and are a diagnostic dilemma. Total excision is complex and relies on combining multiple disciplines including imaging, immunohistochemistry, and adjunct radiation therapy. Long-term follow-up and early detection are key to better outcomes and reduced recurrence.
脊索瘤是一种罕见的肿瘤，起源于脊索残余组织，通常位于中轴骨骼。发生在下颈椎的脊索瘤很罕见。
我们报告一例79岁男性病例，该患者颈部左侧出现肿块，提示下颈椎区域出现了不寻常的脊索瘤表现。本报告描述了该因左侧颈部肿块就医的患者的临床、放射学和组织学检查结果。包括免疫组织化学和活检在内的其他诊断测试证实了存在累及下颈椎区域的脊索瘤。
颈椎脊索瘤诊断的准确性取决于影像学研究结果以及组织学检查（通常通过活检和免疫组织化学）所提供的确认。颈椎脊索瘤的主要治疗方法是手术切除。辅助治疗，如放射治疗，在某些情况下还有化疗，可用于处理残留疾病或复发性肿瘤。
该病例强调了下颈椎脊索瘤的罕见性，其表现为颈部肿块，是一个诊断难题。完全切除很复杂，依赖于包括影像学、免疫组织化学和辅助放射治疗在内的多学科联合。长期随访和早期检测是获得更好结果和降低复发率的关键。
