Birkeland Peter, Hansen Victoria, Tharmabalan Vinosha, Lauritsen Jens, Nielsen Troels, Truelsen Thomas, Rosenbaum Sverre, von Weitzel-Mudersbach Paul
Department of Neurosurgery, Copenhagen University Hospital, Copenhagen, Denmark.
Department of Neurology, Aalborg University Hospital, Aalborg, Denmark.
Acta Neurochir Suppl. 2025;136:93-97. doi: 10.1007/978-3-031-89844-0_11.
Moyamoya disease (MMD) is considered to run a progressive course, but little is known about its long-term outcomes. We conducted a structured phone interview to assess outcomes in a mixed cohort of conservatively and surgically treated patients a median of 9 years and up to 27 years after a diagnosis of MMD. We found that 60% of patients had a favorable outcome (modified Rankin Scale score <3), with only 16% of adult patients working full time. We conclude that MMD considerably impacts daily life in a substantial number of those affected, with only a minority able to provide for themselves.
烟雾病（MMD）被认为呈进行性病程，但对其长期预后知之甚少。我们进行了一次结构化电话访谈，以评估一组经保守治疗和手术治疗的混合队列患者在诊断为烟雾病后中位9年至长达27年的预后情况。我们发现，60%的患者预后良好（改良Rankin量表评分<3），只有16%的成年患者全职工作。我们得出结论，烟雾病对大量患者的日常生活有相当大的影响，只有少数患者能够自给自足。
