Sun Xiaoru, Zhang Xinrong, Liu Muyun
Department of Infectious Disease, NO. 905 Hospital of PLA Navy Affiliated to Naval Medical University, Shanghai 200052, China.
Department of Gastroenterology, National Clinical Research Center for Digestive Diseases, Changhai Hospital, National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai 200433, China.
ILIVER. 2024 Oct 30;3(4):100125. doi: 10.1016/j.iliver.2024.100125. eCollection 2024 Dec.
A recent study by Xiong Yu-Ting and colleagues has unveiled the clinical characteristics and risk factors of acute drug-induced liver injury (DILI). Upon reading the article, we found that there are some differences between female and male patients with DILI in terms of clinical and pathological features, especially in the number of patients, the degree of liver inflammation, and the risk of autoimmune liver disease. Therefore, it is necessary to pay attention to female patients with DILI and their outcomes, and to intervene appropriately in advance. This article analyzes the reasons for the differences between female and male patients with DILI and makes recommendations for patient prognosis.
熊宇婷及其同事最近的一项研究揭示了急性药物性肝损伤（DILI）的临床特征和危险因素。阅读该文章后，我们发现DILI女性和男性患者在临床和病理特征方面存在一些差异，尤其是在患者数量、肝脏炎症程度以及自身免疫性肝病风险方面。因此，有必要关注DILI女性患者及其预后，并提前进行适当干预。本文分析了DILI女性和男性患者存在差异的原因，并对患者预后提出建议。
