Alyassin Nizar, Habib Ruba, Pelidis Michael, Michael Patrick
Department of Internal Medicine, St. Joseph's Regional Medical Center, Paterson, USA.
Eur J Case Rep Intern Med. 2025 Jun 6;12(7):005546. doi: 10.12890/2025_005546. eCollection 2025.
Primary hyperparathyroidism is a very well-documented and understood endocrine pathology that includes the overproduction of parathyroid hormone, leading to an exaggerated effect of hypercalcemia. However, its prevalence leading to pancreatitis, specifically in pregnant patients, is underreported and widely undiagnosed. In this case, we present a case of a 23-year-old female in her second pregnancy who presented with pancreatitis after already being treated and diagnosed with pancreatitis in her first pregnancy. It was later discovered that this patient had a nodule believed to be a parathyroid adenoma. We believe this parathyroid adenoma alone could have gone unnoticed, but with concurrent changes and physiology of pregnancy, caused a significant burden of pancreatitis on our patient, not only in one pregnancy, but in both of her pregnancies.
Hyperparathyroidism is rarely diagnosed in pregnancy and is widely unrecognized.This carries threats to mother and baby, which include pancreatitis.If a parathyroid adenoma is present, surgical removal in the second trimester is the preferred treatment.
原发性甲状旁腺功能亢进是一种记录充分且广为人知的内分泌疾病,其特征是甲状旁腺激素分泌过多,导致高钙血症的影响加剧。然而,其导致胰腺炎的患病率,尤其是在孕妇中,报告不足且广泛未被诊断。在此病例中,我们介绍了一名23岁的女性,她在第二次怀孕时出现了胰腺炎,而她在第一次怀孕时就已经接受过胰腺炎的治疗和诊断。后来发现该患者有一个结节,被认为是甲状旁腺腺瘤。我们认为,仅这个甲状旁腺腺瘤可能未被发现,但由于怀孕时并发的变化和生理状况,给我们的患者带来了严重的胰腺炎负担,不仅在一次怀孕中,而且在她的两次怀孕中都是如此。
甲状旁腺功能亢进在孕期很少被诊断出来,并且广泛未被认识到。这对母婴构成威胁,其中包括胰腺炎。如果存在甲状旁腺腺瘤,在孕中期进行手术切除是首选治疗方法。