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肝细胞癌中的放射组学/放射基因组学：介入治疗中的应用与挑战

Radiomics/Radiogenomics in hepatocellular carcinoma: Applications and challenges in interventional management.

作者信息

Fu Jia, Cao Shou-Jin, Song Li, Tong Xiao-Qiang, Wang Jian, Yang Min, Zou Ying-Hua

机构信息

Department of Interventional Radiology and Vascular Surgery, Peking University First Hospital, Beijing, China.

出版信息

ILIVER. 2022 Aug 1;1(2):96-100. doi: 10.1016/j.iliver.2022.07.001. eCollection 2022 Jun.

DOI:10.1016/j.iliver.2022.07.001
PMID:40636414
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12212588/
Abstract

Hepatocellular carcinoma is one of the leading causes of cancer-related death worldwide. Recently, radiomics and radiogenomics have been introduced as novel dimensions in oncology research. In the current review, we summarize the clinical applications of radiomics and radiogenomics in hepatocellular carcinoma.

摘要

肝细胞癌是全球癌症相关死亡的主要原因之一。近年来，放射组学和放射基因组学已作为肿瘤学研究的新维度被引入。在本综述中，我们总结了放射组学和放射基因组学在肝细胞癌中的临床应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35f/12212588/9974b65cb295/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35f/12212588/fbf2cfdfc369/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35f/12212588/9974b65cb295/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35f/12212588/fbf2cfdfc369/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35f/12212588/9974b65cb295/gr2.jpg

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本文引用的文献

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Radiomics for the detection of microvascular invasion in hepatocellular carcinoma.基于影像组学的肝细胞癌微血管侵犯检测
World J Gastroenterol. 2022 May 28;28(20):2176-2183. doi: 10.3748/wjg.v28.i20.2176.
2
Efficacy and safety of radiotherapy plus anti-PD1 versus transcatheter arterial chemoembolization plus sorafenib for advanced hepatocellular carcinoma: a real-world study.放疗联合抗 PD-1 与经导管动脉化疗栓塞联合索拉非尼治疗晚期肝细胞癌的疗效和安全性：一项真实世界研究。
Radiat Oncol. 2022 Jun 11;17(1):106. doi: 10.1186/s13014-022-02075-6.
3
Improving Adjuvant Liver-Directed Treatment Recommendations for Unresectable Hepatocellular Carcinoma: An Artificial Intelligence-Based Decision-Making Tool.
基于人工智能的决策工具改善不可切除肝细胞癌的辅助肝靶向治疗推荐。
JCO Clin Cancer Inform. 2022 Jun;6:e2200024. doi: 10.1200/CCI.22.00024.
4
Precision interventional radiology.精准介入放射学
J Interv Med. 2021 Dec 23;4(4):155-158. doi: 10.1016/j.jimed.2021.09.002. eCollection 2021 Nov.
5
Multi-Region Radiomic Analysis Based on Multi-Sequence MRI Can Preoperatively Predict Microvascular Invasion in Hepatocellular Carcinoma.基于多序列磁共振成像的多区域放射组学分析可术前预测肝细胞癌微血管侵犯
Front Oncol. 2022 Apr 27;12:818681. doi: 10.3389/fonc.2022.818681. eCollection 2022.
6
MR Imaging Biomarkers for the Prediction of Outcome after Radiofrequency Ablation of Hepatocellular Carcinoma: Qualitative and Quantitative Assessments of the Liver Imaging Reporting and Data System and Radiomic Features.磁共振成像生物标志物预测肝细胞癌射频消融治疗后的结局：肝脏影像报告和数据系统的定性和定量评估及放射组学特征。
J Vasc Interv Radiol. 2022 Jul;33(7):814-824.e3. doi: 10.1016/j.jvir.2022.04.006. Epub 2022 Apr 20.
7
Autophagy-Related Signatures as Prognostic Indicators for Hepatocellular Carcinoma.自噬相关特征作为肝细胞癌的预后指标
Front Oncol. 2022 Mar 24;12:654449. doi: 10.3389/fonc.2022.654449. eCollection 2022.
8
Radiomics models for preoperative prediction of microvascular invasion in hepatocellular carcinoma: a systematic review and meta-analysis.用于术前预测肝细胞癌微血管侵犯的影像组学模型：一项系统评价与荟萃分析
Abdom Radiol (NY). 2022 Jun;47(6):2071-2088. doi: 10.1007/s00261-022-03496-3. Epub 2022 Apr 1.
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BMC Cancer. 2022 Mar 24;22(1):320. doi: 10.1186/s12885-022-09357-y.
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J Pers Med. 2022 Mar 10;12(3):436. doi: 10.3390/jpm12030436.