全脑及突触亚组分中的钙结合蛋白。
Calcium-binding proteins in whole brain and synaptic subfractions.
作者信息
Anthony F A, Babitch J A
出版信息
Brain Res. 1985 Oct 14;345(1):124-31. doi: 10.1016/0006-8993(85)90842-x.
PMID:4063797
Abstract
At least 19 calcium-binding proteins were detected in avian brain subfraction using 45Ca2+ binding to proteins immobilized in polyacrylamide gels. Half of the 45Ca2+ binding proteins were observed in presynaptic cytoplasm. Two-dimensional gel electrophoresis of this material revealed at least 14 45Ca2+ binding polypeptides besides calmodulin. These proteins may be important in brain and nerve terminal function.
摘要
利用45Ca2+与固定在聚丙烯酰胺凝胶中的蛋白质结合，在禽脑亚组分中检测到至少19种钙结合蛋白。45Ca2+结合蛋白的一半在突触前细胞质中观察到。该物质的二维凝胶电泳显示，除钙调蛋白外，至少还有14种45Ca2+结合多肽。这些蛋白质可能在脑和神经末梢功能中起重要作用。
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