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[突触结构的特定蛋白质]

[Specific proteins of synaptic structures].

作者信息

Glebov R N, Kryzhanovskiĭ G N

出版信息

Ukr Biokhim Zh. 1977 Mar-Apr;49(2):117-28.

PMID:867531
Abstract

The article deals with the data concerning localization, properties and functions of specific proteins of nerve endings, especially in the synaptic vesicles and synaptic membranes, as well as concerning their metabolism. In the fractions of the synaptic vesicles and synaptic membranes simple and conjugated proteins (glycoproteids) typical of these high-specialized structures only are localized. Acid polypeptides, contractile proteins and neurospecific proteins of S-100, 14-3-2 type and glycoproteids are such specific proteins of the studied structures. Their possible function in the mechaninsm of secretion and circulation of mediators in synapses is discussed.

摘要

本文论述了有关神经末梢特定蛋白质的定位、特性和功能的数据,特别是突触小泡和突触膜中的蛋白质,以及它们的代谢。在突触小泡和突触膜的组分中,仅定位了这些高度特化结构所特有的简单蛋白质和结合蛋白质(糖蛋白)。酸性多肽、收缩蛋白以及S - 100、14 - 3 - 2型神经特异性蛋白和糖蛋白是这些研究结构的特定蛋白质。文中讨论了它们在突触中介质分泌和循环机制中的可能作用。

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