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痛风患者的手部功能:与类风湿关节炎患者及健康人群的对比研究

Hand function in gout: a comparative study with rheumatoid arthritis and healthy.

作者信息

Mete Oguzhan, Apaydin Hakan, Varol Fatmagül, Gülöksüz Emine Gözde Aydemir, Pamukcu Melih

机构信息

University of Health Sciences, Gülhane Faculty of Physiotherapy and Rehabilitation - Ankara, Turkey.

Etlik City Hospital, Department of Rheumatology - Ankara, Turkey.

出版信息

Rev Assoc Med Bras (1992). 2025 Jul 7;71(6):e20250054. doi: 10.1590/1806-9282.20250054. eCollection 2025.

DOI:10.1590/1806-9282.20250054
PMID:40638474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12245048/
Abstract

OBJECTIVE

The aim of the study was to compare the hand function (grip strength and grip endurance, manual dexterity, and perceived hand functional disability) of participants with gout, rheumatoid arthritis, and healthy control.

METHODS

Grip strength and grip endurance were assessed using a hand dynamometer, while manual dexterity was evaluated through the Nine-Hole Peg Test. Perceived hand functional disability was measured using the Duruöz Hand Index.

RESULTS

The grip strength was similar between gout and healthy control (p>0.05). Dominant and non-dominant grip endurance in gout were lower than healthy control (p=0.008, p=0.001). The dominant placing, removing, and total Nine-Hole Peg Test time of gout compared to healthy control were higher (p=0.001, p<0.001, and p<0.001). The non-dominant placing, removing, and total Nine-Hole Peg Test time of gout were higher than healthy control (p=0.002, p=0.004, and p=0.002). The Duruöz Hand Index in gout was higher than healthy control (p=0.002), but lower than rheumatoid arthritis (p=0.008).

CONCLUSION

Our findings indicate that individuals with gout experience impairments in grip strength, manual dexterity, and perceived hand function. Assessing hand function during clinical examinations of patients with gout should be considered.

摘要

目的

本研究旨在比较痛风患者、类风湿关节炎患者和健康对照者的手部功能(握力和握力耐力、手动灵活性以及手部功能障碍感知)。

方法

使用握力计评估握力和握力耐力,通过九孔插钉试验评估手动灵活性。使用杜罗兹手部指数测量手部功能障碍感知。

结果

痛风患者和健康对照者的握力相似(p>0.05)。痛风患者优势手和非优势手的握力耐力均低于健康对照者(p=0.008,p=0.001)。与健康对照者相比,痛风患者优势手放置、移除插钉及九孔插钉试验总时间更长(p=0.001,p<0.001,p<0.001)。痛风患者非优势手放置、移除插钉及九孔插钉试验总时间高于健康对照者(p=0.002,p=0.004,p=0.002)。痛风患者的杜罗兹手部指数高于健康对照者(p=0.002),但低于类风湿关节炎患者(p=0.008)。

结论

我们的研究结果表明,痛风患者在握力、手动灵活性和手部功能感知方面存在损害。在痛风患者的临床检查中应考虑对手部功能进行评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e30/12245048/7bb083f918a6/1806-9282-ramb-71-06-e20250054-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e30/12245048/7bb083f918a6/1806-9282-ramb-71-06-e20250054-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e30/12245048/7bb083f918a6/1806-9282-ramb-71-06-e20250054-gf01.jpg

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Rheumatol Ther. 2024 Oct;11(5):1271-1290. doi: 10.1007/s40744-024-00697-8. Epub 2024 Aug 5.
2
Validity and reliability of the Duruöz Hand Index in patients with psoriatic arthritis.Duruöz手部指数在银屑病关节炎患者中的有效性和可靠性。
Rheumatol Int. 2024 Mar;44(3):535-542. doi: 10.1007/s00296-023-05517-w. Epub 2024 Jan 9.
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Living with gout. Experiences, impact and challenges of the disease. Qualitative study through focus groups.
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Reumatol Clin (Engl Ed). 2023 Mar;19(3):150-158. doi: 10.1016/j.reumae.2022.03.002. Epub 2022 Sep 2.
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Grip endurance in patients with rheumatoid arthritis: Its relationship between clinical characteristics, upper extremity functional disability, and quality of life.类风湿关节炎患者的握力耐力:其与临床特征、上肢功能障碍和生活质量的关系。
Int J Rheum Dis. 2022 Sep;25(9):1060-1067. doi: 10.1111/1756-185X.14384. Epub 2022 Jul 7.
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Clin Biomech (Bristol). 2022 May;95:105640. doi: 10.1016/j.clinbiomech.2022.105640. Epub 2022 Apr 4.
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