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抗炎药物对儿童面部牙源性蜂窝织炎的影响:法国的一项横断面研究。

The impact of anti-inflammatory drugs on facial odontogenic cellulitis in children: a cross-sectional study in France.

作者信息

Poure Lucille, Delfosse Caroline, Trentesaux Thomas, Maury Fleur, Dubos François, Nicot Romain, Marquillier Thomas

机构信息

Private Practice, Versailles, France.

Université Lille, CHU Lille, UFR3S-Odontologie, Odontologie pédiatrique, Lille, France.

出版信息

BDJ Open. 2025 Jul 10;11(1):64. doi: 10.1038/s41405-025-00351-7.

Abstract

OBJECTIVE

Dental caries is defined by the WHO as a multifactorial non-communicable disease. If left untreated, it can progress to abscesses and then head and neck odontogenic cellulitis. It requires immediate, appropriate, and interdisciplinary treatment. The aim of this study was to draw up an epidemiological profile of these children treated at the Lille University Hospital in northern France and to study the impact of self-medication of anti-inflammatory drugs.

MATERIALS AND METHODS

A single-centre retrospective, cross-sectional study was conducted on children with odontogenic cellulitis admitted to the paediatric emergency department of the Lille University Hospital between March 2013 and December 2021.

RESULTS

15.3% of the 636 children included had taken nonsteroidal anti-inflammatory drugs before going to the emergency department. The frequency of pain and trismus was higher in children who had taken nonsteroidal anti-inflammatory drugs than in those who had not. Frequency of hospitalisation was higher in children who had not taken nonsteroidal anti-inflammatory drugs than for those who had (70% vs. 57%, respectively; p < 0.05). Inversely, the mean length of stay was longer for children who had taken nonsteroidal anti-inflammatory drugs than in those who had not (1.1 vs. 0.8 days, respectively; p < 0.05).

CONCLUSION

This first French epidemiological study on odontogenic cellulitis in children underlines the need to develop multidisciplinary prevention and patient education.

摘要

目的

世界卫生组织将龋齿定义为一种多因素非传染性疾病。如果不进行治疗,它会发展为脓肿,进而引发头颈部牙源性蜂窝织炎。这需要立即进行适当的多学科治疗。本研究的目的是梳理出法国北部里尔大学医院接受治疗的这些儿童的流行病学概况,并研究使用抗炎药物进行自我药疗的影响。

材料与方法

对2013年3月至2021年12月间入住里尔大学医院儿科急诊科的牙源性蜂窝织炎患儿进行了一项单中心回顾性横断面研究。

结果

纳入研究的636名儿童中,15.3%在前往急诊科之前服用过非甾体抗炎药。服用非甾体抗炎药的儿童疼痛和牙关紧闭的发生率高于未服用者。未服用非甾体抗炎药的儿童住院频率高于服用者(分别为70%和57%;p<0.05)。相反,服用非甾体抗炎药的儿童平均住院时间比未服用者更长(分别为1.1天和0.8天;p<0.05)。

结论

这项关于儿童牙源性蜂窝织炎的首次法国流行病学研究强调了开展多学科预防和患者教育的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd4/12246418/52c2b65d41b8/41405_2025_351_Fig1_HTML.jpg

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