Burt R W
Cancer Detect Prev. 1985;8(3):393-8.
The evidence that an adenomatous polyp identifies a patient at higher than average risk for colonic cancer seems firm. There is also growing evidence that polypectomy with followup decreases the expected mortality from colonic cancer in patients with adenomatous polyps. Recent studies suggest inheritance of solitary adenomas and colonic cancer in some pedigrees. Further studies of adenoma etiology are suggested; the information to be gained from such studies should be of potential importance to colonic cancer screening efforts.
腺瘤性息肉可确定患者患结肠癌的风险高于平均水平，这一证据似乎确凿。越来越多的证据表明，对腺瘤性息肉患者进行息肉切除并随访可降低结肠癌的预期死亡率。最近的研究表明，在一些家系中，孤立性腺瘤和结肠癌存在遗传现象。建议进一步开展腺瘤病因学研究；此类研究获得的信息对于结肠癌筛查工作可能具有重要意义。
