Wong Newton A C S, Hunt Linda P, Novelli Marco R, Shepherd Neil A, Warren Bryan F
Department of Clinical Sciences at South Bristol, University of Bristol, Bristol, UK.
Histopathology. 2009 Jul;55(1):63-6. doi: 10.1111/j.1365-2559.2009.03329.x.
To assess observer agreement in the diagnosis of colorectal serrated polyps, in particular, serrated adenomas and admixed polyps (i.e. 'polyps with admixed hyperplastic and adenomatous glands').
Sixty cases of large bowel polyps were assessed by four specialist gastrointestinal histopathologists and allocated into one of five categories: serrated adenoma, hyperplastic polyp, conventional adenoma, admixed polyp, and other polyps with serration. Complete agreement amongst all four assessors was seen with only two-fifths of the cases. The overall kappa value for all the assessors distinguishing between all five categories was 0.49. The kappa values for diagnosing serrated adenoma versus all other polyps, and admixed polyp versus all other polyps were 0.38 and 0.3, respectively.
Specialist gastrointestinal histopathologists show only moderate concordance when distinguishing between serrated colorectal polyps. There is only fair interobserver agreement in the diagnosis of serrated adenomas and admixed polyps of the large bowel.
评估在结直肠锯齿状息肉（特别是锯齿状腺瘤和混合性息肉，即“具有增生性和腺瘤性腺管混合的息肉”）诊断中观察者之间的一致性。
四位胃肠组织病理学专家对60例大肠息肉进行评估，并分为五类之一：锯齿状腺瘤、增生性息肉、传统腺瘤、混合性息肉和其他有锯齿的息肉。所有四位评估者之间完全一致的情况仅见于五分之二的病例。所有评估者区分这五类息肉的总体kappa值为0.49。诊断锯齿状腺瘤与所有其他息肉的kappa值，以及诊断混合性息肉与所有其他息肉的kappa值分别为0.38和0.3。
胃肠组织病理学专家在区分结直肠锯齿状息肉时仅表现出中等程度的一致性。在大肠锯齿状腺瘤和混合性息肉的诊断中，观察者之间的一致性仅为一般。
