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Granuloma annulare treated with certolizumab following the development of antidrug antibodies to adalimumab.

作者信息

Rubenstein Ayelet I, Chung Jina, Rosenbach Misha

机构信息

Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

出版信息

JAAD Case Rep. 2025 Apr 11;61:154-156. doi: 10.1016/j.jdcr.2025.03.028. eCollection 2025 Jul.

DOI:10.1016/j.jdcr.2025.03.028
PMID:40641628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12242322/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d21f/12242322/1b517727c0ee/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d21f/12242322/1b517727c0ee/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d21f/12242322/1b517727c0ee/gr1.jpg

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本文引用的文献

1
Improvement of generalized granuloma annulare with adalimumab: A case report.阿达木单抗治疗泛发性环状肉芽肿疗效观察：1例报告
SAGE Open Med Case Rep. 2024 Feb 16;12:2050313X241231427. doi: 10.1177/2050313X241231427. eCollection 2024.
2
Results of a treatment algorithm for generalized granuloma annulare.
J Am Acad Dermatol. 2024 Feb;90(2):377-380. doi: 10.1016/j.jaad.2023.09.050. Epub 2023 Sep 27.
3
Pegylation Reduces the Uptake of Certolizumab Pegol by Dendritic Cells and Epitope Presentation to T-Cells.聚乙二醇化降低了树突状细胞对培戈珠单抗的摄取和抗原呈递给 T 细胞。
Front Immunol. 2022 Feb 4;13:808606. doi: 10.3389/fimmu.2022.808606. eCollection 2022.
4
The role of biologics in the treatment of chronic granuloma annulare.生物制剂在慢性环状肉芽肿治疗中的作用。
Int J Dermatol. 2019 May;58(5):622-626. doi: 10.1111/ijd.14350. Epub 2019 Jan 7.
5
Quantitative comparison of the neutralizing capacity, immunogenicity and cross-reactivity of anti-TNF-α biologicals and an Infliximab-biosimilar.抗 TNF-α 生物制剂与英夫利昔单抗生物类似药的中和能力、免疫原性和交叉反应性的定量比较。
PLoS One. 2018 Dec 11;13(12):e0208922. doi: 10.1371/journal.pone.0208922. eCollection 2018.
6
Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study.依奇珠单抗与阿达木单抗治疗类风湿关节炎的头对头比较：来自随机 EXXELERATE 研究的 2 年疗效和安全性结果。
Lancet. 2016 Dec 3;388(10061):2763-2774. doi: 10.1016/S0140-6736(16)31651-8. Epub 2016 Nov 15.
7
Granuloma annulare: Pathogenesis, disease associations and triggers, and therapeutic options.环状肉芽肿：发病机制、疾病相关性和触发因素以及治疗选择。
J Am Acad Dermatol. 2016 Sep;75(3):467-479. doi: 10.1016/j.jaad.2015.03.055.
8
Granuloma annulare: Clinical and histologic variants, epidemiology, and genetics.环状肉芽肿：临床和组织学变异型、流行病学和遗传学。
J Am Acad Dermatol. 2016 Sep;75(3):457-465. doi: 10.1016/j.jaad.2015.03.054.
9
Treatment of recalcitrant granuloma annulare (GA) with adalimumab: A single-center, observational study.阿达木单抗治疗难治性环状肉芽肿（GA）：一项单中心观察性研究。
J Am Acad Dermatol. 2016 Jan;74(1):127-33. doi: 10.1016/j.jaad.2015.09.015. Epub 2015 Nov 6.
10
Development of antidrug antibodies against adalimumab and association with disease activity and treatment failure during long-term follow-up.抗阿达木单抗抗体的产生与长期随访期间疾病活动度和治疗失败的关系。
JAMA. 2011 Apr 13;305(14):1460-8. doi: 10.1001/jama.2011.406.