Ninkuu Vincent, Aluko Oluwaseun Olayemi, Yan Jianpei, Zeng Hongmei, Liu Guodao, Zhao Jun, Li Huihui, Chen Songbi, Dakora Felix Dapare
National Nanfan Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Sanya, China.
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences (CAAS), Beijing, China.
Front Plant Sci. 2025 Jun 26;16:1571825. doi: 10.3389/fpls.2025.1571825. eCollection 2025.
The phenylpropanoid pathway remains a key target for most climate-resilient crop development, owing to it being a precursor to over 8000 metabolites, including flavonoids and lignin compounds, including their derivatives. These metabolites are involved in biotic and abiotic stress tolerance, inviting several studies into their roles in plant defense, drought, temperature, UV, and nutrient stress tolerance. Literature is currently inundated with cutting-edge reports on the phenylpropanoid pathways and their functions. Here, we provide a comprehensive update on the biosynthesis of phenylpropanoids, mainly lignin and flavonoids, their roles in biotic and abiotic interaction, and transcending topics, including pest and diseases, drought, temperature, and UV stress tolerance. We further reviewed the post-transcriptional, post-translational, and epigenetic modifications regulating phenylpropanoid metabolism and highlighted their applications and optimization strategies for large-scale production. This review provides an all-inclusive update on recent reports on the metabolism of phenylpropanoids in plants.
苯丙烷类途径仍然是大多数抗气候变化作物培育的关键目标，因为它是8000多种代谢产物的前体，包括类黄酮和木质素化合物及其衍生物。这些代谢产物参与生物和非生物胁迫耐受性，引发了多项关于它们在植物防御、干旱、温度、紫外线和养分胁迫耐受性中作用的研究。目前，关于苯丙烷类途径及其功能的前沿报道充斥着文献。在此，我们全面更新了苯丙烷类化合物（主要是木质素和类黄酮）的生物合成、它们在生物和非生物相互作用中的作用，以及超越这些主题的内容，包括病虫害、干旱、温度和紫外线胁迫耐受性。我们还综述了调节苯丙烷类代谢的转录后、翻译后和表观遗传修饰，并强调了它们在大规模生产中的应用和优化策略。本综述全面更新了关于植物中苯丙烷类代谢的最新报道。
