Wang Yuanhao, Hou Yi, Zhang Jingyu, Guo Kunfeng, Luo Jinyu, Li Shengnan, Mu Gang
Department of Urology, The Fourth People's Hospital of Shenyang, Shenyang, Liaoning, China.
Front Oncol. 2025 Jun 26;15:1527574. doi: 10.3389/fonc.2025.1527574. eCollection 2025.
Metastasis of gastric adenocarcinoma typically involves the liver, peritoneum, and lymph nodes, whereas scrotal wall metastasis is extremely rare, with very few cases reported in the literature. We report a case of a 60-year-old male patient who presented with right-sided scrotal swelling. The patient had previously undergone total gastrectomy and multiple chemotherapy sessions for gastric adenocarcinoma. In June 2024, the scrotal wall metastasis of gastric adenocarcinoma was confirmed. The patient underwent excision of the right scrotal lesion, spermatic cord excision, and right epididymis and testis resection. Immunohistochemical markers, such as CK20, CK7, and CDX-2, were positive, which supported the diagnosis of metastatic gastric adenocarcinoma. Follow-up three months post-surgery showed no evidence of tumor recurrence.
胃腺癌转移通常累及肝脏、腹膜和淋巴结，而阴囊壁转移极为罕见，文献报道的病例很少。我们报告一例60岁男性患者，其表现为右侧阴囊肿胀。该患者此前因胃腺癌接受了全胃切除术和多次化疗。2024年6月，确诊为胃腺癌阴囊壁转移。患者接受了右侧阴囊病变切除、精索切除以及右侧附睾和睾丸切除。免疫组化标志物，如CK20、CK7和CDX-2呈阳性，支持转移性胃腺癌的诊断。术后三个月随访显示无肿瘤复发迹象。
