Pan Hui, Yu Bao-Fu
Clinical Pharmacology Research Center, Peking Union Medical College Hospital, State Key Laboratory of Complex Severe and Rare Diseases, NMPA Key Laboratory for Clinical Research and Evaluation of Drug, Beijing Key Laboratory of Clinical PK & PD Investigation for Innovative Drugs, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing.
Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
J Craniofac Surg. 2025 Jul 11. doi: 10.1097/SCS.0000000000011657.
This study aims to examine the safety and efficacy of using scalp complex tissue combined with subcutaneous adipose tissue for the repair of defects after the excision of upper lip nevus.
The authors conducted a retrospective study involving 8 patients who underwent transplantation of scalp composite tissue with subcutaneous adipose tissue for the reconstruction of upper lip defects after the excision of nevus. The surgical protocol entailed meticulous excision of pathologic skin lesions from the upper lip to adequately prepare the recipient site; subsequently, composite scalp tissue with subcutaneous adipose tissue was harvested from behind the ear and meticulously transplanted to rectify the upper lip deficiency. A comprehensive review of photographic evidence and clinical records for these patients was undertaken. In addition, we evaluated the patients' self-reported satisfaction with the outcomes of their repairs.
Three males and 5 females were included with median age 28 years. All the patients successfully underwent effective wound repair. There were no instances of necrosis observed in the scalp composite tissue during the early postoperative period. The wounds on the lips exhibited complete healing within 2 weeks after surgery. The mean duration of follow-up was 13 months, ranging from 11 to 17 months. All patients expressed profound satisfaction with the clinical outcomes.
It is a safe and effective approach to utilize scalp complex tissue with subcutaneous adipose tissue for the reconstruction of defects arising from the excision of upper lip nevi. The authors propose this method as a viable alternative therapeutic option.
Level Ⅳ.
本研究旨在探讨使用头皮复合组织联合皮下脂肪组织修复上唇痣切除术后缺损的安全性和有效性。
作者进行了一项回顾性研究,纳入8例患者,这些患者接受了带皮下脂肪组织的头皮复合组织移植,以重建上唇痣切除术后的缺损。手术方案包括从上唇仔细切除病理性皮肤病变以充分准备受区;随后,从耳后获取带皮下脂肪组织的复合头皮组织并仔细移植以矫正上唇缺损。对这些患者的照片证据和临床记录进行了全面回顾。此外,我们评估了患者对修复结果的自我报告满意度。
纳入3例男性和5例女性,中位年龄28岁。所有患者均成功接受了有效的伤口修复。术后早期头皮复合组织未观察到坏死情况。唇部伤口在术后2周内完全愈合。平均随访时间为13个月,范围为11至17个月。所有患者对临床结果均表示高度满意。
使用带皮下脂肪组织的头皮复合组织重建上唇痣切除术后的缺损是一种安全有效的方法。作者提出该方法作为一种可行的替代治疗选择。
Ⅳ级。