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首发精神病中的社会逆境与孤独感

Social adversity and loneliness in first episode psychosis.

作者信息

Botello Renata, Gandhi Arti, Grunfeld Gil, Wagner Nicholas J, Oh Hans, Mueser Kim T, Fulford Daniel

机构信息

Department of Psychological and Brain Sciences, Boston University, 635 Commonwealth Ave., SAR-556, Boston, MA, 02215, USA.

Sargent College of Health & Rehabilitation Sciences, Boston University, Boston, USA.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2025 Jul 11. doi: 10.1007/s00127-025-02958-5.

Abstract

PURPOSE

Social adversity-including poverty, trauma, and other adverse life experiences-is associated with higher risk of psychosis and poorer outcomes in schizophrenia spectrum disorders. Loneliness, the subjective experience of social disconnection, is also prevalent among people with psychosis; however, the extent to which social adversity contributes to loneliness in people with psychosis is relatively unknown.

METHODS

In the current study, we developed a measurement model of social adversity and assessed associations with loneliness in 404 participants with First Episode Psychosis (FEP) enrolled in the Recovery After an Initial Schizophrenia Episode-Early Treatment Program. Loneliness was measured using five self-report items (e.g., "I often feel lonely because I have few close friends with whom to share my concerns."). We created a latent variable of social adversity that included trauma history (number of reported traumatic experiences), parental education, homelessness, contact with law enforcement, and deferral/food stamp receipt. We first evaluated our measurement model of social adversity, then estimated a path model of its relationship with loneliness, accounting for age, diagnosis, gender, and degree of recent social involvement. Models were fit at both baseline and six-month timepoints.

RESULTS

The measurement model of social adversity had acceptable fit, with adequate item loadings. At baseline, greater social adversity was associated with limited social involvement and higher self-reported loneliness, though the latter association was not statistically significant. At six months, greater social adversity was associated with significantly greater loneliness.

CONCLUSION

Social adversity may be an important contributor to loneliness in FEP. Such adversity could contribute to feelings of social disconnection by way of either limited opportunities for meaningful social contact, or perceived discrimination/stigma. Psychosocial treatment of FEP should incorporate an understanding of the impact of social adversity on important outcomes in this population.

摘要

目的

社会逆境,包括贫困、创伤和其他不良生活经历,与精神分裂症谱系障碍中患精神病的风险较高及预后较差相关。孤独,即社交隔离的主观体验,在患有精神病的人群中也很普遍;然而,社会逆境在多大程度上导致了精神病患者的孤独感,相对来说还不清楚。

方法

在本研究中,我们建立了一个社会逆境的测量模型,并评估了404名首次发作精神病(FEP)患者的社会逆境与孤独感之间的关联,这些患者参加了首次精神分裂症发作后早期治疗项目的康复研究。孤独感通过五个自我报告项目进行测量(例如,“我经常感到孤独,因为我几乎没有亲密的朋友可以分享我的担忧。”)。我们创建了一个社会逆境的潜在变量,包括创伤史(报告的创伤经历数量)、父母教育程度、无家可归、与执法部门的接触以及延期/领取食品券情况。我们首先评估了社会逆境的测量模型,然后估计了其与孤独感关系的路径模型,同时考虑了年龄、诊断、性别和近期社交参与程度。模型在基线和六个月时间点进行拟合。

结果

社会逆境的测量模型拟合度可接受,项目负荷适当。在基线时,更大的社会逆境与有限的社交参与和更高的自我报告孤独感相关,尽管后者的关联在统计学上不显著。在六个月时,更大的社会逆境与显著更高的孤独感相关。

结论

社会逆境可能是FEP患者孤独感的一个重要促成因素。这种逆境可能通过有意义的社交接触机会有限或感知到的歧视/污名化导致社交隔离感。FEP的心理社会治疗应纳入对社会逆境对该人群重要结局影响的理解。

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