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一项观察性、前瞻性、多中心队列研究中的驴和杂交种麻醉死亡率

Donkey and Hybrid Anaesthetic Mortality in an Observational, Prospective, Multicentre Cohort Study.

作者信息

Boocock Hannah, Flyps Jana, Escobar André, Redondo José I, Taylor Polly M, Gozalo-Marcilla Miguel, Johnston G Mark, Bettschart-Wolfensberger Regula, Sullivan Rebekah

机构信息

Veterinary Department, The Donkey Sanctuary, Exeter EX14 9SU, UK.

Department of Large Animal Surgery, Anaesthesia and Orthopaedics, University of Ghent, Salisburylaan 133, 9820 Merelbeke, Belgium.

出版信息

Animals (Basel). 2025 Jun 25;15(13):1880. doi: 10.3390/ani15131880.

Abstract

Equid anaesthetic mortality is of interest to practitioners. Data for donkey and hybrid mortality have not been specifically described. The main aim of this worldwide observational, prospective, multicentre cohort study was to report on mortality in the 7 days following a general anaesthetic or standing sedation in donkeys and hybrids. This study hypothesised that donkeys and hybrids would have higher mortalities compared to horses. Data were collected as part of the fourth Confidential Enquiry into Perioperative Equine Fatalities (CEPEF4). A total of 825 cases were included, with 757 donkeys and 68 hybrids. Overall, 616 donkeys and 56 hybrids underwent a general anaesthetic. The overall mortality rate for general anaesthesia in donkeys was 1.0% and 3.6% in hybrids. In total, 141 standing sedations were performed in donkeys and 12 in hybrids. Mortality rates for standing sedations were lower, with the donkey mortality rate as 0.7%, and no hybrid mortality was seen. The mortality for donkeys for general anaesthesia appeared similar to the horse, whilst hybrid mortality was higher. COLIC vs. NON-COLIC DEATHs and EUTHANASIAs were also examined in the study. Mortality for standing sedations was lower compared to general anaesthesia. However, the numbers are too low to draw definitive conclusions; further investigation is required.

摘要

马属动物麻醉死亡率是从业者关注的问题。关于驴和杂交马死亡率的数据尚未有具体描述。这项全球范围内的观察性、前瞻性、多中心队列研究的主要目的是报告驴和杂交马在全身麻醉或站立镇静后7天内的死亡率。本研究假设驴和杂交马的死亡率会高于马。数据作为第四次围手术期马属动物死亡情况保密调查(CEPEF4)的一部分收集。总共纳入了825例病例,其中有757头驴和68匹杂交马。总体而言,616头驴和56匹杂交马接受了全身麻醉。驴全身麻醉的总体死亡率为1.0%,杂交马为3.6%。总共对141头驴和12匹杂交马进行了站立镇静。站立镇静的死亡率较低,驴的死亡率为0.7%,未观察到杂交马死亡。驴全身麻醉的死亡率似乎与马相似,而杂交马的死亡率更高。该研究还对因急腹症与非急腹症导致的死亡和安乐死情况进行了检查。站立镇静的死亡率低于全身麻醉。然而,由于数量过少无法得出明确结论;需要进一步调查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09b1/12248588/8d7736e57c56/animals-15-01880-g001.jpg

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