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用于体外研究的下颌全口无牙模拟模型的三维制造——概念与验证

Three-Dimensional Manufacturing of Mandibular Total Edentulous Simulation Model for In Vitro Studies-Concept and Validation.

作者信息

Mendes Joana, Manzanares-Céspedes Maria Cristina, Esteves José L, Fonseca João, Coelho Lara, Mendes José Manuel

机构信息

UNIPRO-Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences IUCS/(CESPU), 4585-116 Gandra, Portugal.

Departament de Patologia i Terapèutica Experimental, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), 08007 Barcelona, Spain.

出版信息

Polymers (Basel). 2025 Jun 30;17(13):1820. doi: 10.3390/polym17131820.

DOI:10.3390/polym17131820
PMID:40647830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12251627/
Abstract

BACKGROUND

Stereolithography is a rapid prototyping and 3D printing technique that creates solid three-dimensional models. An accurate and functional 3D model using stereolithography is invaluable in scientific research, particularly in studies involving edentulous patients. Additive manufacture and CAD systems help achieve accurate measurements and procedures and be easily replicated by lowering human error mistakes. The main objective of this study was to develop an in vitro simulation model with a reduced alveolar ridge with the same characteristics as mandibular edentulous patients using stereolithography.

METHODS

A mandibular model with a resorbed mandibular crest was scanned, and the STL model was aligned to the XYZ reference system. A reduction in the alveolar ridge corresponding to the mandibular mucosa of an edentulous patient was achieved. A negative model also derived from the original model was made to ensure the space for oral simulation material. A dimensional stability test was performed to validate the model.

RESULTS

The maximal mean displacement of the model was 0.015 mm, and the minimal mean displacement was 0.004 mm. The oral mucosa had a displacement of approximately 1.6 mm.

CONCLUSIONS

An in vitro 3D simulation model of a complete edentulous patient mucosa was achieved.

摘要

背景

立体光刻是一种快速成型和3D打印技术,可创建实心三维模型。使用立体光刻技术制作的精确且实用的3D模型在科学研究中具有极高价值,尤其是在涉及无牙患者的研究中。增材制造和CAD系统有助于实现精确测量和操作,并通过减少人为误差而易于复制。本研究的主要目的是使用立体光刻技术开发一种体外模拟模型,该模型具有与下颌无牙患者相同特征的牙槽嵴减小情况。

方法

扫描一个下颌嵴吸收的下颌模型,并将STL模型与XYZ参考系统对齐。实现了与无牙患者下颌黏膜相对应的牙槽嵴减小。还从原始模型制作了一个负模型,以确保口腔模拟材料的空间。进行了尺寸稳定性测试以验证该模型。

结果

模型的最大平均位移为0.015毫米,最小平均位移为0.004毫米。口腔黏膜的位移约为1.6毫米。

结论

获得了无牙患者完整黏膜的体外3D模拟模型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/6da6bda63b28/polymers-17-01820-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/5669d3e46f6e/polymers-17-01820-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/84b7d00199fc/polymers-17-01820-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/5f350d7c150a/polymers-17-01820-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/351d8976b1d7/polymers-17-01820-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/bd83aa9ace04/polymers-17-01820-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/16af90eb0a15/polymers-17-01820-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/1b92346bfe32/polymers-17-01820-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/878d3b512385/polymers-17-01820-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/6da6bda63b28/polymers-17-01820-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/5669d3e46f6e/polymers-17-01820-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/84b7d00199fc/polymers-17-01820-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/5f350d7c150a/polymers-17-01820-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/351d8976b1d7/polymers-17-01820-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/bd83aa9ace04/polymers-17-01820-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/16af90eb0a15/polymers-17-01820-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/1b92346bfe32/polymers-17-01820-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/878d3b512385/polymers-17-01820-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f50/12251627/6da6bda63b28/polymers-17-01820-g009.jpg

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