Heredia Severino Arsenio, Fernández-López Juana, Borrás-Rocher Fernando, Viuda-Martos Manuel
Facultad de Ciencias Agronómicas y Veterinarias, Universidad Autónoma de Santo Domingo-UASD, Santo Domingo 10105, Dominican Republic.
Instituto Dominicano de Investigaciones Agropecuarias y Forestales-IDIAF, Santo Domingo 10205, Dominican Republic.
Plants (Basel). 2025 Jun 20;14(13):1903. doi: 10.3390/plants14131903.
, commonly known as epazote, is a medicinal plant of great relevance in traditional Latin American medicine. Its cultural roots and pharmacological properties have made it an object of study for phytochemical research. An artificial intelligence (AI) tool was utilized to assist in reviewing scientific information regarding . An initial search was conducted in the Scopus database using the keywords epazote, , anti-helminthic, antioxidant, and antimicrobial, which yielded a total of 814 publications. To select the most relevant articles, this AI tool based on natural language processing (available online and free of charge) was applied, which analyzed the keywords that appeared in the titles and abstracts of the works and clustered them, leading to a reduction of 86.73% in the number of studies. stands out for its rich composition of bioactive compounds, which give the plant a wide range of therapeutic properties, including antiparasitic activity, through which it is effective against several parasites, such as helminths and protozoa, due to its schistosomicidal, nematocidal and antimalarial action. Additionally, it has shown antimicrobial, antioxidant, and anticancer properties as it contains compounds that help fight cell damage caused by free radicals. Epazote represents a rich source of compounds with a wide therapeutic range. However, much research is required to understand the mechanisms of action of these compounds and to evaluate their safety and efficacy in clinical trials.
，通常被称为土荆芥，是一种在拉丁美洲传统医学中具有重要意义的药用植物。其文化根源和药理特性使其成为植物化学研究的对象。利用一种人工智能（AI）工具协助审查有关的科学信息。最初在Scopus数据库中使用关键词土荆芥、、抗蠕虫、抗氧化剂和抗菌剂进行搜索，共获得814篇出版物。为了选择最相关的文章，应用了这种基于自然语言处理的AI工具（在线可用且免费），该工具分析了作品标题和摘要中出现的关键词并进行聚类，使研究数量减少了86.73%。以其丰富的生物活性化合物组成而著称，这些化合物赋予该植物广泛的治疗特性，包括抗寄生虫活性，由于其杀血吸虫、杀线虫和抗疟作用，它对几种寄生虫如蠕虫和原生动物有效。此外，它还表现出抗菌、抗氧化和抗癌特性，因为它含有有助于对抗自由基引起的细胞损伤的化合物。土荆芥是具有广泛治疗范围的化合物的丰富来源。然而，需要进行大量研究来了解这些化合物的作用机制，并评估它们在临床试验中的安全性和有效性。
