Robotnik Kinga, Zieliński Tomasz, Walczak-Skierska Justyna, Sibińska Ewelina, Rudzik Paulina, Piszczek Piotr, Radtke Aleksandra, Pomastowski Paweł Piotr
Centre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Toruń, Wileńska 4 Str., 87-100 Toruń, Poland.
Energy Efficiency Project Coordination Team, ORLEN S.A., Chemików 7 Str., 09-411 Płock, Poland.
Nanomaterials (Basel). 2025 Jun 23;15(13):973. doi: 10.3390/nano15130973.
Laser desorption/ionization techniques, such as matrix-assisted laser desorption/ionization (MALDI) and surface-assisted laser desorption/ionization (SALDI), are the basis of modern mass spectrometry, enabling the analysis of a wide range of chemical compounds, from small molecules to biopolymers. MALDI uses organic matrices to support ionization, while SALDI relies on inorganic surfaces or nanomaterials, which reduce background and improve measurement sensitivity. This review focuses on the potential of using silver nanoparticles (AgNPs) in LDI-MS, with particular emphasis on their synthesis from the gas phase (CVD, Chemical Vapor Deposition). The key role of nanostructures in increasing ionization efficiency and analytical selectivity is emphasized. The CVD technique enables precise control over the morphology, size, and distribution of nanoparticles, which translates into better repeatability and sensitivity of nanostructure-assisted laser desorption/ionization mass spectrometry (NALDI-MS) measurements. The latest achievements in this field are presented, as well as potential applications of CVD-produced AgNPs in analytical chemistry, environmental analysis, and the petrochemical industry.
激光解吸/电离技术，如基质辅助激光解吸/电离（MALDI）和表面辅助激光解吸/电离（SALDI），是现代质谱分析的基础，能够分析从小分子到生物聚合物等广泛的化合物。MALDI使用有机基质来支持电离，而SALDI则依赖于无机表面或纳米材料，这可以减少背景并提高测量灵敏度。本综述重点关注在激光解吸电离质谱（LDI-MS）中使用银纳米颗粒（AgNPs）的潜力，特别强调其气相合成（化学气相沉积，CVD）。强调了纳米结构在提高电离效率和分析选择性方面的关键作用。CVD技术能够精确控制纳米颗粒的形态、尺寸和分布，这转化为纳米结构辅助激光解吸/电离质谱（NALDI-MS）测量更好的重复性和灵敏度。介绍了该领域的最新成果，以及CVD制备的AgNPs在分析化学、环境分析和石化工业中的潜在应用。
