Hoang Manh Trung, Bui Huy, Hoang Thi Hong Cam, Pham Van Hai, Loan Nguyen Thu, Le Long Van, Pham Thanh Binh, Duc Chinh Vu, Do Thuy Chi, Kim Tae Jung, Pham Van Hoi, Nguyen Thuy Van
Institute of Materials Science, Vietnam Academy of Science and Technology, Hanoi 100000, Vietnam.
Graduate University of Sciences and Technology, Vietnam Academy of Science and Technology, Hanoi 100000, Vietnam.
Nanomaterials (Basel). 2025 Jun 30;15(13):1007. doi: 10.3390/nano15131007.
In this study, we present a novel surface-enhanced Raman scattering (SERS) substrate based on porous silicon microcavities (PSiMCs) decorated with silver nanoparticles (AgNPs) for ultra-sensitive molecule detection. This substrate utilizes a dual enhancement mechanism: the localized surface plasmon resonance (LSPR) of AgNPs and the optical resonance of the PSiMC structure, which together create intense electromagnetic hot spots and prolong photon-molecule interactions. The porous architecture provides a large surface area for uniform nanoparticle distribution and efficient analyte adsorption. The AgNP/PSiMC substrate demonstrates an impressive detection limit of 1.0 × 10 M for rhodamine101 and 1.0 × 10 M for methyl parathion, outperforming many previously reported SERS platforms. Furthermore, the substrate exhibits excellent signal uniformity (RSD ≈ 6.14%) and long-term stability, retaining over 50% signal intensity after 28 days. These results underscore the potential of AgNP/PSiMCs as highly efficient, reproducible, and scalable SERS platforms for trace-level chemical and environmental sensing applications.
在本研究中，我们展示了一种基于装饰有银纳米颗粒（AgNPs）的多孔硅微腔（PSiMCs）的新型表面增强拉曼散射（SERS）基底，用于超灵敏分子检测。该基底利用了双重增强机制：AgNPs的局域表面等离子体共振（LSPR）和PSiMC结构的光学共振，它们共同产生强烈的电磁热点并延长光子 - 分子相互作用。多孔结构为纳米颗粒的均匀分布和分析物的有效吸附提供了大表面积。AgNP/PSiMC基底对罗丹明101的检测限低至1.0×10⁻¹¹ M，对甲基对硫磷的检测限为1.0×10⁻¹² M，优于许多先前报道的SERS平台。此外，该基底表现出优异的信号均匀性（相对标准偏差≈6.14%）和长期稳定性，在28天后仍保留超过50%的信号强度。这些结果突出了AgNP/PSiMCs作为用于痕量化学和环境传感应用的高效、可重现且可扩展的SERS平台的潜力。
