Cheng Long, Gong Shuhong, Tuersun Paerhatijiang
School of Physics, Xidian University, Xi'an 710071, China.
Xinjiang Key Laboratory for Luminescence Minerals and Optical Functional Materials, School of Physics and Electronic Engineering, Xinjiang Normal University, Urumqi 830054, China.
Nanomaterials (Basel). 2025 Jul 6;15(13):1052. doi: 10.3390/nano15131052.
Previous investigations devoted to non-spherical nanoparticles for biosensing have primarily addressed two hot topics, namely, finding nanoparticles with the best shape for refractive index sensing properties and the optimization of size parameters. In this study, based on these hot topics, Au-Ag alloy nanoparticles with excellent optical properties were selected as the research object. Targeting rotationally symmetric Au-Ag alloy nanoparticles for biosensing applications, the complex media function correction model and T-matrix approach were used to systematically analyze the variation patterns of extinction properties, refractive index sensitivity, full width at half maximum, and figure of merit of three rotationally symmetric Au-Ag alloy nanoparticles with respect to the size of the particles and the Au molar fraction. In addition, we optimized the figure of merit to obtain the best size parameters and Au molar fractions for the three rotationally symmetric Au-Ag alloy nanoparticles. Finally, the range of dimensional parameters corresponding to a figure of merit greater than 98% of its maximum value was calculated. The results show that the optimized Au-Ag alloy nanorods exhibit a refractive index sensitivity of 395.2 nm/RIU, a figure of merit of 7.16, and a wide range of size parameters. Therefore, the optimized Au-Ag alloy nanorods can be used as high-performance biosensors. Furthermore, this study provides theoretical guidance for the application and preparation of rotationally symmetric Au-Ag alloy nanoparticles in biosensing.
先前针对用于生物传感的非球形纳米颗粒的研究主要涉及两个热门话题，即寻找具有最佳形状以实现折射率传感特性的纳米颗粒以及优化尺寸参数。在本研究中，基于这些热门话题，选择具有优异光学特性的金-银合金纳米颗粒作为研究对象。针对用于生物传感应用的旋转对称金-银合金纳米颗粒，使用复介质函数校正模型和T矩阵方法系统地分析了三种旋转对称金-银合金纳米颗粒的消光特性、折射率灵敏度、半高宽和品质因数随颗粒尺寸和金摩尔分数的变化规律。此外，我们对品质因数进行了优化，以获得三种旋转对称金-银合金纳米颗粒的最佳尺寸参数和金摩尔分数。最后，计算了品质因数大于其最大值98%时对应的尺寸参数范围。结果表明，优化后的金-银合金纳米棒表现出395.2 nm/RIU的折射率灵敏度、7.16的品质因数以及较宽的尺寸参数范围。因此，优化后的金-银合金纳米棒可作为高性能生物传感器。此外，本研究为旋转对称金-银合金纳米颗粒在生物传感中的应用和制备提供了理论指导。
