Ciancarelli Irene, Martino Cinnera Alex, Ricci Alessandro, Iosa Marco, Cerasa Antonio, Calabrò Rocco Salvatore, Morone Giovanni
Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
IRCCS Santa Lucia Foundation Hospital, 00179 Rome, Italy.
J Clin Med. 2025 Jun 20;14(13):4391. doi: 10.3390/jcm14134391.
Limited research has examined the relationship between preoperative health status and health-related quality of life (HRQoL) in patients with lumbar spinal stenosis (LSS) undergoing surgery. This study aims to assess the role of clinical, preoperative health and demographic factors on short-term HRQoL and functional outcomes following LSS surgery. : A longitudinal study was conducted on 61 LSS patients (mean age 72.2 ± 8.8 years) undergoing surgery, assessing HRQoL and clinical outcomes before and 30 days post-surgery. Demographic and preoperative health status data were collected at baseline. HRQoL was measured using the Short Form Health Survey 36 (SF-36); clinical evaluations included assessments of disability, pain, and psychological status. Changes in HRQoL and clinical scores were analyzed with repeated measures ANOVA. HRQoL improvement was correlated with demographic and clinical variables, using Pearson's correlation. : Spinal surgery for LSS led to significant improvements in HRQoL, with notable gains in both physical and mental health components (both < 0.001), and in particular, in the body pain (+34%) and physical functioning, role physical, and social functioning (+20%) subscales of SF-36. Clinical scores also showed significant post-surgery improvements, strongly correlating with HRQoL. Correlations between ΔSF-36 subscale scores and preoperative factors revealed negative associations with BMI, smoking, comorbidities, and psychological distress. Conversely, physical activity was positively correlated with HRQoL improvements, especially in items showing the greatest score increases. : Surgical treatment for LSS determines a significant improvement in HRQoL and functional outcome, which are however influenced by preoperative factors such as psychological distress, high BMI, smoking, and comorbidities. Conversely, regular physical activity is associated with better daily functioning, work performance, and social engagement. A comprehensive preoperative assessment may be a useful and appropriate tool to identify patients who are most likely to benefit and optimize quality of life after LSS surgery.
有限的研究探讨了接受手术的腰椎管狭窄症（LSS）患者术前健康状况与健康相关生活质量（HRQoL）之间的关系。本研究旨在评估临床、术前健康和人口统计学因素对LSS手术后短期HRQoL和功能结局的作用。：对61例接受手术的LSS患者（平均年龄72.2±8.8岁）进行了一项纵向研究，评估术前和术后30天的HRQoL和临床结局。在基线时收集人口统计学和术前健康状况数据。使用简短健康调查问卷36（SF-36）测量HRQoL；临床评估包括对残疾、疼痛和心理状态的评估。采用重复测量方差分析分析HRQoL和临床评分的变化。使用Pearson相关性分析HRQoL改善与人口统计学和临床变量之间的相关性。：LSS的脊柱手术使HRQoL得到显著改善，身心健康成分均有显著提高（均P<0.001），特别是在SF-36的身体疼痛（+34%）、身体功能、角色身体和社会功能（+20%）子量表方面。临床评分术后也显示出显著改善，与HRQoL密切相关。ΔSF-36子量表评分与术前因素之间的相关性显示，与体重指数、吸烟、合并症和心理困扰呈负相关。相反，身体活动与HRQoL改善呈正相关，尤其是在得分增加最大的项目中。：LSS的手术治疗可显著改善HRQoL和功能结局，但受心理困扰、高体重指数、吸烟和合并症等术前因素影响。相反，规律的身体活动与更好的日常功能、工作表现和社会参与度相关。全面的术前评估可能是识别最有可能从LSS手术中获益并优化生活质量的患者的有用且合适的工具。
