Song Fuyan, Wang Zixun, Zhang Xiaoling, Yu Zhenjie, Li Zhiqing
Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.
Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China; Handan Eye Hospital (The Third Hospital of Handan), Hebei, China.
Acta Psychol (Amst). 2025 Aug;258:105264. doi: 10.1016/j.actpsy.2025.105264. Epub 2025 Jul 11.
Intravitreal injections (IVIs) are essential yet anxiety-provoking procedures. This study evaluates the impact of perioperative music interventions on mitigating anxiety and hemodynamic responses.
To explore the influence of various music genres on anxiety and blood pressure (BP) levels in patients undergoing IVI at the day-surgery center.
This study was a randomized controlled trial involving 130 patients who were scheduled to receive IVI. The participants were randomly assigned to one of four groups: the binaural beat group (n = 31), the Chinese music group (n = 33), the Western music group (n = 31), and the control group (n = 35). Patients in the music groups were provided with in-ear headphones and received corresponding musical interventions in the waiting room and throughout the surgery, while the control group did not receive any special interventions. Before the operation, all participants completed the State-Trait Anxiety Inventory (STAI-S) questionnaire, systolic BP (SBP), diastolic BP (DBP), and pulse rate (PR) were measured, which were measured during and after surgery as well. After the IVI operation, the STAI-S questionnaire was again filled out completely.
The cohort (59.2 % female; mean age 62.22 ± 12.71 years) exhibited baseline measures of STAI-S (39.38 ± 5.77), SBP (148.88 ± 19.67 mmHg), DBP (81.82 ± 10.93 mmHg), and PR (82.97 ± 11.53 bpm). Post-intervention, significant reductions in STAI-S scores occurred in the binaural beats group (-7.23 ± 3.83; P < 0.001 vs control) and Chinese music group (-4.12 ± 5.02; P = 0.018 vs control), while the binaural beats group uniquely attenuated SBP elevation (intraoperative: P = 0.019; postoperative: P < 0.005 vs other groups). No significant changes emerged in DBP or pulse rate across groups (P > 0.05).
Among the Chinese population, both binaural beats and Chinese music were found to significantly reduce anxiety levels in patients receiving IVIs. Furthermore, the binaural beats group exhibited a decrease in systolic blood pressure during and after the procedure. Music therapy may be potentially advantageous for improving the perioperative period of IVIs in patients. In the future, the combined magic of music therapy and ophthalmic surgery should be explored to reduce anxiety in patients with ophthalmic diseases themselves.
玻璃体内注射(IVI)是必不可少但又令人焦虑的操作。本研究评估围手术期音乐干预对减轻焦虑和血流动力学反应的影响。
探讨不同音乐类型对日间手术中心接受玻璃体内注射患者焦虑和血压(BP)水平的影响。
本研究为一项随机对照试验,纳入130例计划接受玻璃体内注射的患者。参与者被随机分为四组之一:双耳节拍组(n = 31)、中国音乐组(n = 33)、西方音乐组(n = 31)和对照组(n = 35)。音乐组的患者佩戴入耳式耳机,在候诊室及整个手术过程中接受相应的音乐干预,而对照组未接受任何特殊干预。手术前,所有参与者完成状态-特质焦虑量表(STAI-S)问卷,测量收缩压(SBP)、舒张压(DBP)和脉搏率(PR),手术期间及术后也进行测量。玻璃体内注射手术后,再次完整填写STAI-S问卷。
该队列(59.2%为女性;平均年龄62.22±12.71岁)的STAI-S基线测量值为(39.38±5.77),SBP为(148.88±19.67mmHg),DBP为(81.82±10.93mmHg),PR为(82.97±11.53次/分钟)。干预后,双耳节拍组(-7.23±3.83;与对照组相比,P<0.001)和中国音乐组(-4.12±5.02;与对照组相比,P = 0.018)的STAI-S评分显著降低,而双耳节拍组独特地减弱了SBP升高(术中:P = 0.019;术后:与其他组相比,P<0.005)。各组间DBP或脉搏率无显著变化(P>0.05)。
在中国人中,发现双耳节拍和中国音乐均可显著降低接受玻璃体内注射患者的焦虑水平。此外,双耳节拍组在手术期间及术后收缩压有所下降。音乐疗法可能对改善玻璃体内注射患者的围手术期有潜在益处。未来,应探索音乐疗法与眼科手术相结合的神奇效果,以减轻眼科疾病患者本身的焦虑。