Wang J, Shi H, White D, Ko H, Paneru D, Sharma M, Patterson R, Kim W K
Department of Poultry Science, University of Georgia, Athens, USA; 30602; Department of Poultry Science, Auburn University, Auburn, USA; 36849.
Department of Poultry Science, University of Georgia, Athens, USA; 30602.
Poult Sci. 2025 Jul 9;104(10):105551. doi: 10.1016/j.psj.2025.105551.
An experiment was conducted to evaluate the effect of liquid yeast cell wall (YCW) supplementation in water on growth performance, intestinal development, immunity, and cecal microbiota in broilers. A total of 360 Cobb 500 male broilers were randomly allocated to three treatments with 6 replicates of 20 birds each. Experimental water treatments consisted of 1) a control (CON) group supplied with municipal water; 2) a liquid yeast cell wall (YCW1) supplemented group during d 0-14 and d 39-42 at 2.5 mL/L; 3) a liquid yeast cell wall (YCW2) supplemented group during d 0-14 and d 39-42 at 5 mL/L. All data were subjected to the one-way ANOVA using the GLM procedure of SAS. Means were further separated using Tukey's HSD test. A significant difference was considered at P ≤ 0.05. Liquid YCW supplementation linearly improved FCR during the d7-14 of age. A quadratic effect on BWG peaks at 2.5 mL/L inclusion rate was found during the d14-21 period. Growth performance was not affected by liquid YCW during 42 d grow-out period. Liquid YCW supplementation linearly increased duodenal villus height (P = 0.014) at d14. Meanwhile, broilers of YCW2 group had a lower villus height: crypt depth ratio (P = 0.037). Supplementation of liquid YCW linearly upregulated the proinflammatory cytokine interferon gamma (IFN-γ) and nuclear factor kappa B (NF-κB) and downregulated anti-inflammatory cytokine interleukin-10 (IL-10) in ceca tonsil compared to the control (P < 0.05). At d 42, YCW2 had a lower Salmonella population in ceca compared to the other treatments (P = 0.021). Additionally, supplementation of liquid YCW increased Lactobacillus population in the ceca compared to the control group (P < 0.01). In conclusion, liquid YCW supplementation positively affected early age growth performance by improving intestinal development. Late-phase supplementation of YCW reduced Salmonella population in the ceca, suggesting YCW as a potential intervention to reduce pre-harvest Salmonella load.
进行了一项实验，以评估在饮水中添加液体酵母细胞壁（YCW）对肉鸡生长性能、肠道发育、免疫力和盲肠微生物群的影响。总共360只科宝500雄性肉鸡被随机分配到三个处理组，每组6个重复，每个重复20只鸡。实验饮水处理包括：1）对照组（CON）供应市政用水；2）在第0至14天和第39至42天以2.5 mL/L添加液体酵母细胞壁（YCW1）的组；3）在第0至14天和第39至42天以5 mL/L添加液体酵母细胞壁（YCW2）的组。所有数据使用SAS的GLM程序进行单因素方差分析。均值进一步使用Tukey's HSD检验进行分离。P≤0.05时认为存在显著差异。在7至14日龄期间，添加液体YCW呈线性改善饲料转化率。在14至21日龄期间，发现添加率为2.5 mL/L时对平均日增重有二次效应峰值。在42天的生长周期中，液体YCW对生长性能没有影响。在第14天，添加液体YCW呈线性增加十二指肠绒毛高度（P = 0.014）。同时，YCW2组的肉鸡绒毛高度与隐窝深度比值较低（P = 0.037）。与对照组相比，添加液体YCW使盲肠扁桃体中促炎细胞因子干扰素γ（IFN-γ）和核因子κB（NF-κB）呈线性上调，抗炎细胞因子白细胞介素-10（IL-10）呈线性下调（P < 0.05）。在第42天，与其他处理相比，YCW2组盲肠中的沙门氏菌数量较低（P = 0.021）。此外，与对照组相比，添加液体YCW增加了盲肠中的乳酸杆菌数量（P < 0.01）。总之，添加液体YCW通过改善肠道发育对早期生长性能产生积极影响。后期添加YCW可降低盲肠中的沙门氏菌数量，表明YCW作为一种潜在干预措施可降低收获前沙门氏菌载量。
