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Cutaneous mucormycosis in a critically ill nonagenarian patient caused by Rhizopus species treated with intravenous isavuconazole and topical amphotericin B along with wound debridement.

作者信息

Wang Ying, Zhang Miaoyan, Hu Haoqi, Han Zhihui, Cui Na, Li Qi

机构信息

Department of Health Care, Peking Union Medical College Hospital, Beijing 100730, PR China.

Department of Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China.

出版信息

Diagn Microbiol Infect Dis. 2025 Nov;113(3):116997. doi: 10.1016/j.diagmicrobio.2025.116997. Epub 2025 Jul 6.

DOI:10.1016/j.diagmicrobio.2025.116997
PMID:40652777
Abstract

This case report highlights cutaneous mucormycosis in a 99-year-old patient who was effectively treated with intravenous isavuconazole and local amphotericin B after wound debridement. The patient showed significant improvement within two weeks, highlighting the importance of diagnosis and treatment for this rare fungal infection. It underscores the need for early recognition and suggests that combining antifungal treatments with surgical intervention may be an optimal strategy, even in patients lacking typical risk factors.

摘要

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