Lowe Christopher D, Sainato Rebecca J, Stagliano David R, Morgan Maribel M, Green Brian P
Department of Dermatology, Walter Reed National Military Medical Center, Bethesda, Maryland.
Department of Pediatric Infectious Diseases, Walter Reed National Military Medical Center, Bethesda, Maryland.
Pediatr Dermatol. 2017 May;34(3):e116-e119. doi: 10.1111/pde.13124.
Cutaneous mucormycosis is a rare but often fatal invasive fungal infection that occurs most commonly in patients with diabetes, malignancy, and other immunocompromising conditions. We report an extremely preterm (<28 weeks) baby boy who developed polymicrobial sepsis and primary cutaneous mucormycosis within his first 10 days of life. He was successfully treated with medical management alone since he was not a candidate for surgery. Successful treatment of cutaneous mucormycosis without surgical debridement has been reported on only two other occasions. This case highlights the importance of rapid and thorough evaluation of skin lesions when evaluating preterm infants and other immunocompromised patients, even when other sources of infection have been identified.
皮肤毛霉病是一种罕见但往往致命的侵袭性真菌感染，最常发生于糖尿病、恶性肿瘤及其他免疫功能低下的患者。我们报告一例极早产儿（<28周）男婴，在出生后的头10天内发生了多微生物败血症和原发性皮肤毛霉病。由于他不适合手术，仅通过药物治疗就成功治愈。此前仅有另外两例报告显示，在未进行手术清创的情况下成功治疗皮肤毛霉病。该病例强调了在评估早产儿和其他免疫功能低下患者时，即使已确定其他感染源，对皮肤病变进行快速、全面评估的重要性。
