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感染蓝氏贾第鞭毛虫的正常及营养不良动物肠道对营养物质的摄取

Intestinal uptake of nutrients in normal and malnourished animals infected with Giardia lamblia.

作者信息

Upadhyay P, Ganguly N K, Mahajan R C, Walia B N

出版信息

Digestion. 1985;32(4):243-8. doi: 10.1159/000199244.

Abstract

The effect of malnutrition on the uptake of nutrients was studied in Swiss albino mice infected with Giardia lamblia. The moderate deficiency (8% protein-deficient diet) was observed to enhance the uptake of nutrients like glucose and alanine, whereas in severely malnourished (3% protein-deficient diet) animals the uptake was significantly decreased (p less than 0.001). G. lamblia infection in mice decreased the uptake of nutrients and this recovered slightly with the recovery of infection. The combined effect of moderate protein deficiency and infection lowered the enhanced uptake observed in moderately malnourished animals to a significant level (p less than 0.001). In severely malnourished animals, infection with G. lamblia showed further deleterious effects on the uptake of nutrients.

摘要

在感染蓝氏贾第鞭毛虫的瑞士白化小鼠中研究了营养不良对营养物质摄取的影响。观察到中度营养不良(8%蛋白质缺乏饮食)会增强葡萄糖和丙氨酸等营养物质的摄取,而在严重营养不良(3%蛋白质缺乏饮食)的动物中,摄取量显著降低(p<0.001)。小鼠感染蓝氏贾第鞭毛虫会降低营养物质的摄取,并且随着感染的恢复略有回升。中度蛋白质缺乏和感染的联合作用将中度营养不良动物中观察到的增强摄取降低到了显著水平(p<0.001)。在严重营养不良的动物中,感染蓝氏贾第鞭毛虫对营养物质的摄取表现出进一步的有害影响。

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