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Glycolysis hijacked: a novel pathogenic role of lipoprotein(a) in valve disease.

作者信息

Weiss Luisa, Aikawa Elena

机构信息

Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, 3 Blackfan Street, Boston, MA 02115, USA.

Center for Excellence in Vascular Biology, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

出版信息

Eur Heart J Open. 2025 Jun 6;5(4):oeaf069. doi: 10.1093/ehjopen/oeaf069. eCollection 2025 Jul.

DOI:10.1093/ehjopen/oeaf069
PMID:40654528
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12246370/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa68/12246370/375680851873/oeaf069f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa68/12246370/375680851873/oeaf069f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa68/12246370/375680851873/oeaf069f1.jpg

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Glycolysis hijacked: a novel pathogenic role of lipoprotein(a) in valve disease.

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[4]
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[5]
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[6]
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[7]
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[8]
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[9]
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[10]
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本文引用的文献

[1]
KAN0438757, a novel PFKFB3 inhibitor, prevent the progression of severe acute pancreatitis via the Nrf2/HO-1 pathway in infiltrated macrophage.

Free Radic Biol Med. 2024-1

[2]
Major Facilitator Superfamily Domain Containing 5 Inhibition Reduces Lipoprotein(a) Uptake and Calcification in Valvular Heart Disease.

Circulation. 2024-1-30

[3]
Lipoprotein(a) and calcific aortic valve disease: current evidence and future directions.

Curr Opin Clin Nutr Metab Care. 2024-1-1

[4]
Plasminogen Receptors Promote Lipoprotein(a) Uptake by Enhancing Surface Binding and Facilitating Macropinocytosis.

Arterioscler Thromb Vasc Biol. 2023-10

[5]
Inclisiran, Low-Density Lipoprotein Cholesterol and Lipoprotein (a).

Pharmaceuticals (Basel). 2023-4-12

[6]
Suppression of PFKFB3-driven glycolysis restrains endothelial-to-mesenchymal transition and fibrotic response.

Signal Transduct Target Ther. 2022-9-1

[7]
PALMD regulates aortic valve calcification via altered glycolysis and NF-κB-mediated inflammation.

J Biol Chem. 2022-5

[8]
Lipoprotein(a) Induces Vesicular Cardiovascular Calcification Revealed With Single-Extracellular Vesicle Analysis.

Front Cardiovasc Med. 2022-1-28

[9]
Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation.

Circ Res. 2020-5-8

[10]
Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis.

J Am Coll Cardiol. 2019-5-7

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