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2019冠状病毒病感染后的休止期脱发:113例回顾性研究

Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases.

作者信息

Chhabra Namrata, George C Anju, Ganguly Satyaki

机构信息

Department of Dermatology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

出版信息

Int J Trichology. 2025 Jan-Feb;17(1):32-35. doi: 10.4103/ijt.ijt_38_22. Epub 2025 Jun 23.

Abstract

BACKGROUND

Telogen effluvium (TE) is self limiting diffuse hair loss occurring 3-4 months after a triggering event. There is scarcity of data on TE as possible sequelae of COVID-19.

METHODS

We assessed 113 cases of TE occurring after SARS-CoV-2 infection as a retrospective study.

RESULTS

Most of the patients belonged to the age group 18-30 years and were females (85.8%). Most of the patients (92%) had acute TE. The median duration of hair loss was 2 months. Trichodynia and pruritus were the common associated complaints. Hair pull test was positive in 54.9% patients. Trichoscopy showed short regrowing hairs in 61.2% patients and empty hair follicles in 77.9% patients. Ferritin, vitamin D and Vitamin B12 deficiency was seen in 27.4%, 38.1% and 20.4% patients respectively. TE was seen more commonly with symptomatic COVID infection (93% patients).

CONCLUSION

TE occurring after SARS-CoV-2 infection calls for assessment of micronutrient deficiency, as there appears to be an association between COVID-19 infection and nutritional deficiency. Although acute TE is the most common presentation, relapse in chronic TE might also occur as sequelae of COVID-19 infection.

摘要

背景

休止期脱发(TE)是一种自限性弥漫性脱发,发生在触发事件后的3 - 4个月。关于TE作为新冠病毒病可能后遗症的数据较少。

方法

我们进行了一项回顾性研究,评估了113例新冠病毒感染后发生的休止期脱发病例。

结果

大多数患者年龄在18 - 30岁之间,且为女性(85.8%)。大多数患者(92%)患有急性休止期脱发。脱发的中位持续时间为2个月。毛发疼痛和瘙痒是常见的相关主诉。54.9%的患者拔毛试验呈阳性。毛发镜检查显示,61.2%的患者有短的再生毛发,77.9%的患者有毛囊空虚。分别有27.4%、38.1%和20.4%的患者存在铁蛋白、维生素D和维生素B12缺乏。休止期脱发在有症状的新冠病毒感染患者中更常见(93%的患者)。

结论

新冠病毒感染后发生的休止期脱发需要评估微量营养素缺乏情况,因为新冠病毒感染与营养缺乏之间似乎存在关联。虽然急性休止期脱发是最常见的表现,但慢性休止期脱发复发也可能作为新冠病毒感染的后遗症出现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/323e/12252012/29ea4939d124/IJT-17-32-g001.jpg

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