Sadique Tuhin, Khan Asif Reza, Ahmed Dilruba, Kabir Fazlul, Chowdhury Anup, Islam Nazrul, Halim Farhana, Akter Nasrin, Islam Shoeb Bin
Clinical Microbiology and Immunology Laboratory Office of Executive Director (OED), icddr,b Dhaka Bangladesh.
Clin Case Rep. 2025 Jul 11;13(7):e70603. doi: 10.1002/ccr3.70603. eCollection 2025 Jul.
is a rare but potentially fatal pathogen found in tropical and subtropical regions. Infections with have rarely been reported in humans, with an exceptionally high mortality rate, particularly when linked to septicemia. We report the case of a 45-year-old female farmer from Bangladesh who developed severe septicemia following an insect bite and subsequent self-drainage of an abscess. Blood cultures identified . The patient was treated empirically with intravenous ciprofloxacin and ceftriaxone, leading to full recovery despite resistance to ceftriaxone. Successful management of infections requires early diagnosis and prompt antimicrobial therapy. The intrinsic resistance mechanism of this organism, including the blaCVI gene associated with Carbapenem resistance, necessitates careful antibiotic selection. The literature review highlights successful cases, depending largely on timely intervention. This case highlights the need for careful antibiotic selection based on clinical response and sensitivity patterns. Moreover, increasing awareness among healthcare professionals, particularly in tropical and subtropical regions, is vital for early detection and successful treatment of this rare, life-threatening infection.
是一种在热带和亚热带地区发现的罕见但可能致命的病原体。人类感染 的情况鲜有报道，死亡率极高，尤其是与败血症相关时。我们报告了一例来自孟加拉国的45岁女性农民病例，她在被昆虫叮咬并随后自行排出脓肿后发生了严重败血症。血培养鉴定出 。患者经验性接受静脉注射环丙沙星和头孢曲松治疗，尽管对头孢曲松耐药，但仍完全康复。成功管理 感染需要早期诊断和及时的抗菌治疗。这种生物体的内在耐药机制，包括与碳青霉烯耐药相关的blaCVI基因，需要谨慎选择抗生素。文献综述强调了成功案例，这在很大程度上取决于及时干预。该病例突出了根据临床反应和药敏模式谨慎选择抗生素的必要性。此外，提高医疗保健专业人员的认识，特别是在热带和亚热带地区，对于早期发现和成功治疗这种罕见的、危及生命的感染至关重要。
