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突尼斯阿卜杜勒拉赫曼·马米医院急诊科新冠病房的新冠长期症状:患病率、主要症状及相关因素

Long COVID symptoms in the COVID unit of the emergency Department of Abderrahmen Mami Hospital in Tunisia: prevalence, main symptoms, and associated factors.

作者信息

Dhaouadi Nawel, Souissi Donia, Yacoub Sarra Ben, Skhiri Afef, Harizi Chahida, Fakhfakh Radhouane, Boujdaria Rafik

机构信息

Department of Epidemiology and Statistics of Abderrahmen Mami Hospital, Ariana, Tunisia.

Department of Emergency of Abderrahmen Mami Hospital, Ariana, Tunisia.

出版信息

Pan Afr Med J. 2025 Apr 23;50:109. doi: 10.11604/pamj.2025.50.109.37221. eCollection 2025.

Abstract

INTRODUCTION

the COVID-19 pandemic has been evolving since 2019, affecting over 536 million individuals and causing more than six million deaths. After the acute phase, the onset or persistence of symptoms grouped under the name of long COVID is reported. The variability of symptomatology makes this a relevant subject of study, since more than one million cases of COVID-19 have been reported in Tunisia. The aim of our study was to determine the prevalence and potential risk factors for long COVID.

METHODS

we conducted a retrospective cohort study of patients admitted to the COVID unit of the emergency department of Abderrahmane Mami Hospital in Tunisia from April 1st to August 1st, 2021. The National Institute of Health Care definition of long COVID (November 2021) was adopted.

RESULTS

overall, 1,271 patients were admitted during the study period. After excluding deceased and unreachable patients by telephone, 454 were included in the analysis. The mean age was 58.6 ± 13.9 years, with a male predominance (53.7%). The prevalence of long COVID was 84.8%. The most common manifestations were breathing discomfort, asthenia, memory problems, tiredness, and arthralgia. In multivariable analysis, female sex was identified as a risk factor for long COVID (aOR: 1.732, 95% CI 1.002-2.995; p = 0.049).

CONCLUSION

the high prevalence of long COVID observed in our study highlights the need for post-COVID follow-up among affected patients. Our findings suggest that women had a higher risk of developing long COVID, indicating the benefit of individualized monitoring and care programs for this group.

摘要

引言

自2019年以来,新冠疫情一直在演变,影响了超过5.36亿人,并导致600多万人死亡。在急性期过后,有报告称出现了以“长新冠”之名归类的症状的发作或持续存在。症状的多样性使这成为一个相关的研究课题,因为突尼斯已报告了超过100万例新冠病例。我们研究的目的是确定长新冠的患病率和潜在风险因素。

方法

我们对2021年4月1日至8月1日在突尼斯阿卜杜勒拉赫曼·马米医院急诊科新冠病房住院的患者进行了一项回顾性队列研究。采用了美国国立卫生研究院对长新冠的定义(2021年11月)。

结果

总体而言,在研究期间有1271名患者入院。在排除死亡患者和通过电话无法联系到的患者后,454名患者被纳入分析。平均年龄为58.6±13.9岁,男性占主导(53.7%)。长新冠的患病率为84.8%。最常见的表现是呼吸不适、乏力、记忆问题、疲劳和关节痛。在多变量分析中,女性被确定为长新冠的一个风险因素(调整后比值比:1.732,95%置信区间1.002 - 2.995;p = 0.049)。

结论

我们研究中观察到的长新冠的高患病率凸显了对受影响患者进行新冠后随访的必要性。我们的研究结果表明,女性患长新冠的风险更高,这表明为该群体制定个性化监测和护理计划的益处。

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