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女性乳腺透明细胞汗腺瘤的诊断挑战:一例报告及术前超声检查在鉴别肿瘤起源中的作用

Challenging diagnosis of clear cell hidradenocarcinoma of the female breast: a case report and the role of pre-operative ultrasonography in differentiating the origin of the tumor.

作者信息

Sangnoppatham Nopparuj, Triamchaipisut Pisit, Wongyongsil Jitpanu, Limlunjakorn Phanop, Thaweepworadej Panya

机构信息

Division of General Surgery, Department of Surgery, Bangkok Metropolitan Administration (BMA) General Hospital, 514 Luang Road, Pom Prap Subdistrict, Pom Prap Sattru Phai District, Bangkok 10100, Thailand.

Department of Anatomical Pathology, Bangkok Metropolitan Administration (BMA) General Hospital, 514 Luang Road, Pom Prap Subdistrict, Pom Prap Sattru Phai District, Bangkok 10100, Thailand.

出版信息

J Surg Case Rep. 2025 Jul 11;2025(7):rjaf491. doi: 10.1093/jscr/rjaf491. eCollection 2025 Jul.

DOI:10.1093/jscr/rjaf491
PMID:40656158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12253956/
Abstract

Clear cell hidradenocarcinoma is a rare neoplasm of the breast that can mimic tumors originating from superficial breast tissue. Early recognition of the tumor's origin is essential for guiding appropriate evaluation and treatment. We report a case involving a 75-year-old patient with hidradenocarcinoma of the breast and highlight the utility of preoperative ultrasonography in differentiating the tumor's origin. Due to the limited data available on the nature of this disease, a modified radical mastectomy was performed following a wide excisional biopsy.

摘要

透明细胞汗腺癌是一种罕见的乳腺肿瘤,可模仿起源于乳腺浅表组织的肿瘤。早期识别肿瘤的起源对于指导适当的评估和治疗至关重要。我们报告了一例涉及一名75岁乳腺汗腺癌患者的病例,并强调术前超声检查在鉴别肿瘤起源方面的作用。由于关于这种疾病性质的可用数据有限,在广泛切除活检后进行了改良根治性乳房切除术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24f8/12253956/9eedc74fb6f5/rjaf491f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24f8/12253956/1b0366654aa3/rjaf491f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24f8/12253956/cab04a6a1f6e/rjaf491f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24f8/12253956/9eedc74fb6f5/rjaf491f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24f8/12253956/1b0366654aa3/rjaf491f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24f8/12253956/cab04a6a1f6e/rjaf491f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24f8/12253956/9eedc74fb6f5/rjaf491f3.jpg

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本文引用的文献

1
Hidradenocarcinoma of the Female Breast: A Surgical Approach to a Rare Skin Tumor.女性乳腺汗腺癌:一种针对罕见皮肤肿瘤的手术治疗方法
Cureus. 2023 Jul 27;15(7):e42577. doi: 10.7759/cureus.42577. eCollection 2023 Jul.
2
Current Diagnosis and Treatment Options for Cutaneous Adnexal Neoplasms with Apocrine and Eccrine Differentiation.具有大汗腺和小汗腺分化的皮肤附件肿瘤的当前诊断和治疗选择。
Int J Mol Sci. 2021 May 11;22(10):5077. doi: 10.3390/ijms22105077.
3
Malignant sweat gland tumor of breast arising in pre-existing benign tumor: A case report.
起源于既往存在的良性肿瘤的乳腺恶性汗腺肿瘤:一例报告
World J Clin Cases. 2019 Oct 6;7(19):3033-3038. doi: 10.12998/wjcc.v7.i19.3033.
4
Hydroadenocarcinoma of clear cells located in the breast.位于乳腺的透明细胞汗腺癌。
Cir Esp (Engl Ed). 2018 May;96(5):308-310. doi: 10.1016/j.ciresp.2017.08.011. Epub 2017 Oct 13.
5
Malignant Clear Cell Hidradenoma of the Breast.乳腺恶性透明细胞汗腺瘤
Cureus. 2017 Mar 1;9(3):e1064. doi: 10.7759/cureus.1064.
6
Current management approach to hidradenocarcinoma: a comprehensive review of the literature.当前汗腺癌的管理方法:文献综述
Ecancermedicalscience. 2015 Mar 19;9:517. doi: 10.3332/ecancer.2015.517. eCollection 2015.
7
Clear cell hidradenocarcinoma of the breast: a very rare breast skin tumor.
Tumori. 2012 Mar-Apr;98(2):43e-45e. doi: 10.1700/1088.11947.
8
Distinguishing breast skin lesions from superficial breast parenchymal lesions: diagnostic criteria, imaging characteristics, and pitfalls.鉴别乳腺皮肤病变与乳腺浅部实质病变:诊断标准、影像学特征及陷阱。
Radiographics. 2011 Nov-Dec;31(7):1959-72. doi: 10.1148/rg.317115116.
9
Cutaneous hidradenocarcinoma: a clinicopathological, immunohistochemical, and molecular biologic study of 14 cases, including Her2/neu gene expression/amplification, TP53 gene mutation analysis, and t(11;19) translocation.皮肤汗腺癌:14例病例的临床病理、免疫组化及分子生物学研究,包括Her2/neu基因表达/扩增、TP53基因突变分析及t(11;19)易位
Am J Dermatopathol. 2009 May;31(3):236-47. doi: 10.1097/DAD.0b013e3181984f10.