Parekh Sneh, Merry Ty J, Tripathi Vanshika, Reddy Pramod
Internal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Cureus. 2025 Jun 13;17(6):e85948. doi: 10.7759/cureus.85948. eCollection 2025 Jun.
Colchicine is a commonly used medication that treats gout, familial Mediterranean fever, and pericarditis. Colchicine overdose is rarely seen; however, toxicity from colchicine overdose can have life-threatening consequences, precipitating multiorgan failure and death. Colchicine toxicity has a unique presentation that can result in severe abdominal pain, rhabdomyolysis, and leukopenia. Early identification of colchicine toxicity is necessary to help guide management, as no specific antidote exists. We present the case of a 31-year-old female who presented with severe abdominal pain and the sequelae of colchicine overdose, along with a discussion regarding her clinical course and management.
秋水仙碱是一种常用药物，用于治疗痛风、家族性地中海热和心包炎。秋水仙碱过量服用很少见；然而，秋水仙碱过量导致的毒性可产生危及生命的后果，引发多器官功能衰竭和死亡。秋水仙碱中毒有独特的表现，可导致严重腹痛、横纹肌溶解和白细胞减少。由于不存在特效解毒剂，早期识别秋水仙碱中毒对于指导治疗很有必要。我们报告一例31岁女性，她因严重腹痛就诊，存在秋水仙碱过量服用的后遗症，并对其临床病程和治疗进行讨论。
